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The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium

CTR9 is the scaffold subunit in polymerase-associated factor complex (PAFc), a multifunctional complex employed in multiple steps of RNA Polymerase II (RNAPII)-mediated transcription. CTR9/PAFc is well known as an evolutionarily conserved elongation factor that regulates gene activation via coupling...

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Detalles Bibliográficos
Autores principales: Chan, Ngai Ting, Huang, Junfeng, Ma, Gui, Zeng, Hao, Donahue, Kristine, Wang, Yidan, Li, Lingjun, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887485/
https://www.ncbi.nlm.nih.gov/pubmed/35137163
http://dx.doi.org/10.1093/nar/gkac047

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