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The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium
CTR9 is the scaffold subunit in polymerase-associated factor complex (PAFc), a multifunctional complex employed in multiple steps of RNA Polymerase II (RNAPII)-mediated transcription. CTR9/PAFc is well known as an evolutionarily conserved elongation factor that regulates gene activation via coupling...
Autores principales: | Chan, Ngai Ting, Huang, Junfeng, Ma, Gui, Zeng, Hao, Donahue, Kristine, Wang, Yidan, Li, Lingjun, Xu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887485/ https://www.ncbi.nlm.nih.gov/pubmed/35137163 http://dx.doi.org/10.1093/nar/gkac047 |
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