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Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas

A sporadic desmoid tumor (DT) is a rare type of tumor of the mesenchymal connective tissues is now considered an intermediate disease or locally aggressive. They may develop on scars or after traumatism, favored by growth factors released during the initial phase of wound healing. Most of the abdomi...

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Autores principales: Damiani, Giovanni, Mikhael, Rabih, Tzanis, Dimitri, El Zein, Sophie, Bonvalot, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887548/
https://www.ncbi.nlm.nih.gov/pubmed/35251801
http://dx.doi.org/10.7759/cureus.21727
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author Damiani, Giovanni
Mikhael, Rabih
Tzanis, Dimitri
El Zein, Sophie
Bonvalot, Sylvie
author_facet Damiani, Giovanni
Mikhael, Rabih
Tzanis, Dimitri
El Zein, Sophie
Bonvalot, Sylvie
author_sort Damiani, Giovanni
collection PubMed
description A sporadic desmoid tumor (DT) is a rare type of tumor of the mesenchymal connective tissues is now considered an intermediate disease or locally aggressive. They may develop on scars or after traumatism, favored by growth factors released during the initial phase of wound healing. Most of the abdominal DT arising on a scar is described on the wall incision. In this report, we describe two cases of DT arising on the intraperitoneal surgical scar, shortly after the resection of a low-grade retroperitoneal liposarcoma and a low-risk gastric gastrointestinal stromal tumor (GIST). Inconsistency between low risk according to the classification of the primary sarcoma and early local recurrence (LR) should raise the possibility of DT. Core needle biopsy (CNB) should be performed when it is feasible, including on local recurrences (LR). Surveillance has become the first-line treatment for DT. In case of progression between two imaging during the surveillance phase, surgery, when it's not mutilating, is indicated for selected cases as second-line treatment.
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spelling pubmed-88875482022-03-03 Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas Damiani, Giovanni Mikhael, Rabih Tzanis, Dimitri El Zein, Sophie Bonvalot, Sylvie Cureus Pathology A sporadic desmoid tumor (DT) is a rare type of tumor of the mesenchymal connective tissues is now considered an intermediate disease or locally aggressive. They may develop on scars or after traumatism, favored by growth factors released during the initial phase of wound healing. Most of the abdominal DT arising on a scar is described on the wall incision. In this report, we describe two cases of DT arising on the intraperitoneal surgical scar, shortly after the resection of a low-grade retroperitoneal liposarcoma and a low-risk gastric gastrointestinal stromal tumor (GIST). Inconsistency between low risk according to the classification of the primary sarcoma and early local recurrence (LR) should raise the possibility of DT. Core needle biopsy (CNB) should be performed when it is feasible, including on local recurrences (LR). Surveillance has become the first-line treatment for DT. In case of progression between two imaging during the surveillance phase, surgery, when it's not mutilating, is indicated for selected cases as second-line treatment. Cureus 2022-01-30 /pmc/articles/PMC8887548/ /pubmed/35251801 http://dx.doi.org/10.7759/cureus.21727 Text en Copyright © 2022, Damiani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Damiani, Giovanni
Mikhael, Rabih
Tzanis, Dimitri
El Zein, Sophie
Bonvalot, Sylvie
Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas
title Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas
title_full Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas
title_fullStr Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas
title_full_unstemmed Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas
title_short Desmoid Tumors Arising on the Mesenteric Surgical Scar of Abdominal Sarcomas
title_sort desmoid tumors arising on the mesenteric surgical scar of abdominal sarcomas
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887548/
https://www.ncbi.nlm.nih.gov/pubmed/35251801
http://dx.doi.org/10.7759/cureus.21727
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