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Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance

Even 30 years after the discovery of the hepatitis C virus (HCV) in humans there is still no vaccine available. Reasons for this include the high mutation rate of HCV, which allows the virus to escape immune recognition and the absence of an immunocompetent animal model for vaccine development. Phyl...

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Detalles Bibliográficos
Autores principales:	Gömer, André, Brown, Richard J P, Pfaender, Stephanie, Deterding, Katja, Reuter, Gábor, Orton, Richard, Seitz, Stefan, Bock, C- Thomas, Cavalleri, Jessika M V, Pietschmann, Thomas, Wedemeyer, Heiner, Steinmann, Eike, Todt, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887644/ https://www.ncbi.nlm.nih.gov/pubmed/35242360 http://dx.doi.org/10.1093/ve/veac007

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