Cargando…

Correlative proteomics identify the key roles of stress tolerance strategies in Acinetobacter baumannii in response to polymyxin and human macrophages

The opportunistic pathogen Acinetobacter baumannii possesses stress tolerance strategies against host innate immunity and antibiotic killing. However, how the host-pathogen-antibiotic interaction affects the overall molecular regulation of bacterial pathogenesis and host response remains unexplored....

Descripción completa

Detalles Bibliográficos
Autores principales:	Kho, Zhi Ying, Azad, Mohammad A. K., Han, Mei-Ling, Zhu, Yan, Huang, Cheng, Schittenhelm, Ralf B., Naderer, Thomas, Velkov, Tony, Selkrig, Joel, Zhou, Qi (Tony), Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887720/ https://www.ncbi.nlm.nih.gov/pubmed/35231068 http://dx.doi.org/10.1371/journal.ppat.1010308

Ejemplares similares

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii
por: Mahamad Maifiah, Mohd Hafidz, et al.
Publicado: (2016)

Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study
por: Tran, Thien B., et al.
Publicado: (2018)

Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against Acinetobacter baumannii: A Metabolomic Study
por: Hussein, Maytham, et al.
Publicado: (2022)

Metabolic Responses to Polymyxin Treatment in Acinetobacter baumannii ATCC 19606: Integrating Transcriptomics and Metabolomics with Genome-Scale Metabolic Modeling
por: Zhu, Yan, et al.
Publicado: (2019)

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii
por: Tran, Thien B., et al.
Publicado: (2015)

Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance
por: Zhu, Yan, et al.
Publicado: (2020)

RapidResa Polymyxin Acinetobacter NP(®) Test for Rapid Detection of Polymyxin Resistance in Acinetobacter baumannii
por: Bouvier, Maxime, et al.
Publicado: (2021)

A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii
por: Jiang, Xukai, et al.
Publicado: (2021)

Rescuing the Last-Line Polymyxins: Achievements and Challenges
por: Nang, Sue C., et al.
Publicado: (2021)

A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii
por: Park, Jaeeun, et al.
Publicado: (2021)

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii
por: Maifiah, Mohd Hafidz Mahamad, et al.
Publicado: (2017)

Editorial Commentary: Polymyxin-Resistant Acinetobacter baumannii: Urgent Action Needed
por: Pogue, Jason M., et al.
Publicado: (2015)

PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo
por: Chauzy, Alexia, et al.
Publicado: (2022)

Comparative Metabolomics Reveals Key Pathways Associated With the Synergistic Killing of Colistin and Sulbactam Combination Against Multidrug-Resistant Acinetobacter baumannii
por: Han, Mei-Ling, et al.
Publicado: (2019)

Strategies for Rapid Identification of Acinetobacter baumannii Membrane Proteins and Polymyxin B’s Effects
por: Lu, Yun, et al.
Publicado: (2021)

Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells
por: Li, Mengyao, et al.
Publicado: (2023)

Combatting Planktonic and Biofilm Populations of Carbapenem-Resistant Acinetobacter baumannii with Polymyxin-Based Combinations
por: Wences, Marisol, et al.
Publicado: (2022)

Novel Polymyxin Combination With Antineoplastic Mitotane Improved the Bacterial Killing Against Polymyxin-Resistant Multidrug-Resistant Gram-Negative Pathogens
por: Tran, Thien B., et al.
Publicado: (2018)

Design and Evaluation of Novel Polymyxin Fluorescent Probes
por: Yun, Bo, et al.
Publicado: (2017)

Sub-minimum inhibitory concentrations of colistin and polymyxin B promote Acinetobacter baumannii biofilm formation
por: Sato, Yoshinori, et al.
Publicado: (2018)

Combination therapy with polymyxin B and netropsin against clinical isolates of multidrug-resistant Acinetobacter baumannii
por: Chung, Joon-hui, et al.
Publicado: (2016)

Polymyxin Induces Significant Transcriptomic Perturbations of Cellular Signalling Networks in Human Lung Epithelial Cells
por: Li, Mengyao, et al.
Publicado: (2022)

Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae
por: Hussein, Maytham, et al.
Publicado: (2023)

Clinically Relevant Concentrations of Polymyxin B and Meropenem Synergistically Kill Multidrug-Resistant Pseudomonas aeruginosa and Minimize Biofilm Formation
por: Wickremasinghe, Hasini, et al.
Publicado: (2021)

Polymyxins–Curcumin Combination Antimicrobial Therapy: Safety Implications and Efficacy for Infection Treatment
por: Dai, Chongshan, et al.
Publicado: (2020)

In vitro antibacterial activity of combinations of fosfomycin, minocycline and polymyxin B on pan-drug-resistant Acinetobacter baumannii
por: ZHANG, YAJUN, et al.
Publicado: (2013)

Hetero- and adaptive resistance to polymyxin B in OXA-23-producing carbapenem-resistant Acinetobacter baumannii isolates
por: Barin, Juliana, et al.
Publicado: (2013)

Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens
por: Cheah, Soon-Ee, et al.
Publicado: (2016)

In vitro and in vivo Activity of Combinations of Polymyxin B with Other Antimicrobials Against Carbapenem-Resistant Acinetobacter baumannii
por: Zhang, Hui, et al.
Publicado: (2021)

6-Bromo-2-naphthol from Silene armeria extract sensitizes Acinetobacter baumannii strains to polymyxin
por: Kang, Mingyeong, et al.
Publicado: (2022)

Polymyxin B, Cefoperazone Sodium-Sulbactam Sodium, and Tigecycline against Multidrug-Resistant Acinetobacter baumannii Pneumonia
por: Hu, Guangxue, et al.
Publicado: (2022)

Metabolomic profiling of polymyxin-B in combination with meropenem and sulbactam against multi-drug resistant Acinetobacter baumannii
por: Zhu, Shixing, et al.
Publicado: (2022)

Metabolomics revealed mechanism for the synergistic effect of sulbactam, polymyxin-B and amikacin combination against Acinetobacter baumannii
por: Zhu, Shixing, et al.
Publicado: (2023)

Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii
por: Han, Mei-Ling, et al.
Publicado: (2018)

Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria
por: Deris, Zakuan Z., et al.
Publicado: (2014)

In-Vitro Activity of Polymyxin B, Rifampicin, Tigecycline Alone and in Combination against Carbapenem-Resistant Acinetobacter baumannii in Singapore
por: Lim, Tze-Peng, et al.
Publicado: (2011)

Successful treatment of extensively drug-resistant Acinetobacter baumannii ventriculitis with polymyxin B and tigecycline- a case report
por: Guo, Wei, et al.
Publicado: (2018)

Impact of minocycline, polymyxin B, meropenem, and amikacin on growth-prevention of Acinetobacter baumannii with various biofilm-forming capabilities
por: Beganovic, Maya, et al.
Publicado: (2017)

Pharmacodynamic evaluation of suppression of in vitro resistance in Acinetobacter baumannii strains using polymyxin B-based combination therapy
por: Fedrigo, Nayara Helisandra, et al.
Publicado: (2021)

In vitro and in vivo Activity of Combinations of Polymyxin B with Other Antimicrobials Against Carbapenem-Resistant Acinetobacter baumannii [Corrigendum]
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_07fqhkip380ipirim0euccv5ok