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Lateralization of bladder function in normal female canines

This study aimed to identify potential lateralization of bladder function. Electrical stimulation of spinal roots or the pelvic nerve’s anterior vesical branch was performed bilaterally in female dogs. The percent difference between the left and right stimulation-induced increased detrusor pressure...

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Autores principales: Giaddui, Dania, Porreca, Danielle S., Tiwari, Ekta, Frara, Nagat A., Hobson, Lucas J., Barbe, Mary F., Braverman, Alan S., Brown, Justin M., Pontari, Michel A., Ruggieri Sr., Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887770/
https://www.ncbi.nlm.nih.gov/pubmed/35231045
http://dx.doi.org/10.1371/journal.pone.0264382
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author Giaddui, Dania
Porreca, Danielle S.
Tiwari, Ekta
Frara, Nagat A.
Hobson, Lucas J.
Barbe, Mary F.
Braverman, Alan S.
Brown, Justin M.
Pontari, Michel A.
Ruggieri Sr., Michael R.
author_facet Giaddui, Dania
Porreca, Danielle S.
Tiwari, Ekta
Frara, Nagat A.
Hobson, Lucas J.
Barbe, Mary F.
Braverman, Alan S.
Brown, Justin M.
Pontari, Michel A.
Ruggieri Sr., Michael R.
author_sort Giaddui, Dania
collection PubMed
description This study aimed to identify potential lateralization of bladder function. Electrical stimulation of spinal roots or the pelvic nerve’s anterior vesical branch was performed bilaterally in female dogs. The percent difference between the left and right stimulation-induced increased detrusor pressure was determined. Bladders were considered left or right-sided if differences were greater or less than 25% or 10%. Based on differences of 25%, upon stimulation of spinal roots, bladders were left-sided in 17/44 (38.6%), right-sided in 12/44 (27.2%) and bilateral in 15/44 (34.2%). Using ± 10%, 48% had left side dominance (n = 21/44), 39% had right side dominance (n = 17/44), and 14% were bilateral (n = 6/44). With stimulation of the pelvic nerve’s anterior vesical branch in 19 dogs, bladders were left-sided in 8 (42.1%), right-sided in 6 (31.6%) and bilateral in 5 (26.3%) using 25% differences and left side dominance in 8 (43%), right sided in 7 (37%) and bilateral in 4 (21%) using 10% differences. These data suggest lateralization of innervation of the female dog bladder with left- and right-sided lateralization occurring at similar rates. Lateralization often varied at different spinal cord levels within the same animal.
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spelling pubmed-88877702022-03-02 Lateralization of bladder function in normal female canines Giaddui, Dania Porreca, Danielle S. Tiwari, Ekta Frara, Nagat A. Hobson, Lucas J. Barbe, Mary F. Braverman, Alan S. Brown, Justin M. Pontari, Michel A. Ruggieri Sr., Michael R. PLoS One Research Article This study aimed to identify potential lateralization of bladder function. Electrical stimulation of spinal roots or the pelvic nerve’s anterior vesical branch was performed bilaterally in female dogs. The percent difference between the left and right stimulation-induced increased detrusor pressure was determined. Bladders were considered left or right-sided if differences were greater or less than 25% or 10%. Based on differences of 25%, upon stimulation of spinal roots, bladders were left-sided in 17/44 (38.6%), right-sided in 12/44 (27.2%) and bilateral in 15/44 (34.2%). Using ± 10%, 48% had left side dominance (n = 21/44), 39% had right side dominance (n = 17/44), and 14% were bilateral (n = 6/44). With stimulation of the pelvic nerve’s anterior vesical branch in 19 dogs, bladders were left-sided in 8 (42.1%), right-sided in 6 (31.6%) and bilateral in 5 (26.3%) using 25% differences and left side dominance in 8 (43%), right sided in 7 (37%) and bilateral in 4 (21%) using 10% differences. These data suggest lateralization of innervation of the female dog bladder with left- and right-sided lateralization occurring at similar rates. Lateralization often varied at different spinal cord levels within the same animal. Public Library of Science 2022-03-01 /pmc/articles/PMC8887770/ /pubmed/35231045 http://dx.doi.org/10.1371/journal.pone.0264382 Text en © 2022 Giaddui et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Giaddui, Dania
Porreca, Danielle S.
Tiwari, Ekta
Frara, Nagat A.
Hobson, Lucas J.
Barbe, Mary F.
Braverman, Alan S.
Brown, Justin M.
Pontari, Michel A.
Ruggieri Sr., Michael R.
Lateralization of bladder function in normal female canines
title Lateralization of bladder function in normal female canines
title_full Lateralization of bladder function in normal female canines
title_fullStr Lateralization of bladder function in normal female canines
title_full_unstemmed Lateralization of bladder function in normal female canines
title_short Lateralization of bladder function in normal female canines
title_sort lateralization of bladder function in normal female canines
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887770/
https://www.ncbi.nlm.nih.gov/pubmed/35231045
http://dx.doi.org/10.1371/journal.pone.0264382
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