Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma

Peritumoral light chain (AL) amyloidosis secondary to lymphoid malignancies is a rare but well-described entity. Peritumoral deposition of amyloid without systemic amyloidosis has been described in mucosa-associated lymphoid tissue (MALT) lymphomas; however, there are no reported cases of follicular...

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Autores principales: Shah, Kalpesh, Kollimuttathuillam, Sudarsan v, Bethel, Nyan, Shaaban, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887873/
https://www.ncbi.nlm.nih.gov/pubmed/35251810
http://dx.doi.org/10.7759/cureus.21738
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author Shah, Kalpesh
Kollimuttathuillam, Sudarsan v
Bethel, Nyan
Shaaban, Hamid
author_facet Shah, Kalpesh
Kollimuttathuillam, Sudarsan v
Bethel, Nyan
Shaaban, Hamid
author_sort Shah, Kalpesh
collection PubMed
description Peritumoral light chain (AL) amyloidosis secondary to lymphoid malignancies is a rare but well-described entity. Peritumoral deposition of amyloid without systemic amyloidosis has been described in mucosa-associated lymphoid tissue (MALT) lymphomas; however, there are no reported cases of follicular lymphoma with localized peritumoral AL amyloidosis without systemic involvement of amyloidosis. We present a rare case of a patient with advanced follicular lymphoma with peritumoral lymph node IgM lambda light chain amyloidosis without an underlying monoclonal gammopathy or plasma cell dyscrasia.
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spelling pubmed-88878732022-03-03 Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma Shah, Kalpesh Kollimuttathuillam, Sudarsan v Bethel, Nyan Shaaban, Hamid Cureus Internal Medicine Peritumoral light chain (AL) amyloidosis secondary to lymphoid malignancies is a rare but well-described entity. Peritumoral deposition of amyloid without systemic amyloidosis has been described in mucosa-associated lymphoid tissue (MALT) lymphomas; however, there are no reported cases of follicular lymphoma with localized peritumoral AL amyloidosis without systemic involvement of amyloidosis. We present a rare case of a patient with advanced follicular lymphoma with peritumoral lymph node IgM lambda light chain amyloidosis without an underlying monoclonal gammopathy or plasma cell dyscrasia. Cureus 2022-01-30 /pmc/articles/PMC8887873/ /pubmed/35251810 http://dx.doi.org/10.7759/cureus.21738 Text en Copyright © 2022, Shah et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Shah, Kalpesh
Kollimuttathuillam, Sudarsan v
Bethel, Nyan
Shaaban, Hamid
Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma
title Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma
title_full Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma
title_fullStr Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma
title_full_unstemmed Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma
title_short Peritumoral Immunoglobulin M Lambda Light Chain Amyloidosis in a Patient With Advanced Follicular Lymphoma
title_sort peritumoral immunoglobulin m lambda light chain amyloidosis in a patient with advanced follicular lymphoma
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887873/
https://www.ncbi.nlm.nih.gov/pubmed/35251810
http://dx.doi.org/10.7759/cureus.21738
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