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The clock modulator Nobiletin mitigates astrogliosis‐associated neuroinflammation and disease hallmarks in an Alzheimer’s disease model

Alzheimer's disease (AD) is a devastating neurodegenerative disorder, and there is a pressing need to identify disease‐modifying factors and devise interventional strategies. The circadian clock, our intrinsic biological timer, orchestrates various cellular and physiological processes including...

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Detalles Bibliográficos
Autores principales: Wirianto, Marvin, Wang, Chih‐Yen, Kim, Eunju, Koike, Nobuya, Gomez‐Gutierrez, Ruben, Nohara, Kazunari, Escobedo, Gabriel, Choi, Jong Min, Han, Chorong, Yagita, Kazuhiro, Jung, Sung Yun, Soto, Claudio, Lee, Hyun Kyoung, Morales, Rodrigo, Yoo, Seung‐Hee, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887996/
https://www.ncbi.nlm.nih.gov/pubmed/35120261
http://dx.doi.org/10.1096/fj.202101633R