Cargando…
The clock modulator Nobiletin mitigates astrogliosis‐associated neuroinflammation and disease hallmarks in an Alzheimer’s disease model
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, and there is a pressing need to identify disease‐modifying factors and devise interventional strategies. The circadian clock, our intrinsic biological timer, orchestrates various cellular and physiological processes including...
Autores principales: | Wirianto, Marvin, Wang, Chih‐Yen, Kim, Eunju, Koike, Nobuya, Gomez‐Gutierrez, Ruben, Nohara, Kazunari, Escobedo, Gabriel, Choi, Jong Min, Han, Chorong, Yagita, Kazuhiro, Jung, Sung Yun, Soto, Claudio, Lee, Hyun Kyoung, Morales, Rodrigo, Yoo, Seung‐Hee, Chen, Zheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887996/ https://www.ncbi.nlm.nih.gov/pubmed/35120261 http://dx.doi.org/10.1096/fj.202101633R |
Ejemplares similares
-
Effects of the Clock Modulator Nobiletin on Circadian Rhythms and Pathophysiology in Female Mice of an Alzheimer’s Disease Model
por: Kim, Eunju, et al.
Publicado: (2021) -
Clock-Modulating Activities of the Anti-Arrhythmic Drug Moricizine
por: Han, Chorong, et al.
Publicado: (2021) -
Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice
por: Nohara, Kazunari, et al.
Publicado: (2019) -
Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge
por: Nohara, Kazunari, et al.
Publicado: (2019) -
Cardiolipin Synthesis in Skeletal Muscle Is Rhythmic and Modifiable by Age and Diet
por: Nohara, Kazunari, et al.
Publicado: (2020)