Cargando…

Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer

OBJECTIVE: To investigate the regulatory effect of ZEB1 on PD-L1 expression and the pharmacodynamic effects of Biochanin A on the malignant biological behaviors of colorectal cancer (CRC). METHODS: The correlation between epithelial-mesenchymal transition (EMT) score and features of the tumor microe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Junying, Yang, Xuejing, Pan, Jiadong, Fan, Honghong, Mei, Jie, Hua, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888121/ https://www.ncbi.nlm.nih.gov/pubmed/35242187 http://dx.doi.org/10.1155/2022/3224373

Ejemplares similares

Biochanin A inhibits lung adenocarcinoma progression by targeting ZEB1
por: Li, Jianjun, et al.
Publicado: (2022)

EHF suppresses cancer progression by inhibiting ETS1-mediated ZEB expression
por: Sakamoto, Kaname, et al.
Publicado: (2021)

Analysis of the Role and Mechanism of ZEB1 in Regulating Cervical Carcinoma Progression via Modulating PD-1/PD-L1 Checkpoint
por: Lin, Yuhong, et al.
Publicado: (2022)

Retracted: Analysis of the Role and Mechanism of ZEB1 in Regulating Cervical Carcinoma Progression via Modulating PD-1/PD-L1 Checkpoint
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Pan‐cancer analysis revealing DAAM1 as a novel predictive biomarker for PD‐1/PD‐L1 blockade in clear cell renal cell carcinoma
por: Mei, Jie, et al.
Publicado: (2022)

LncRNA ZEB1‐AS1 down‐regulation suppresses the proliferation and invasion by inhibiting ZEB1 expression in oesophageal squamous cell carcinoma
por: Zhao, Yan, et al.
Publicado: (2019)

Expression and Function of ZEB1 in the Cornea
por: Zhang, Yingnan, et al.
Publicado: (2021)

Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A
por: Sordon, Sandra, et al.
Publicado: (2017)

High expression of ZEB1 is associated with EMAST & metastasis in colorectal cancer patients
por: Mohammadpour, Somayeh, et al.
Publicado: (2022)

Vitamin D deficiency contributes to the diabetic kidney disease progression via increase ZEB1/ZEB2 expressions
por: Souza, Cláudia Silva, et al.
Publicado: (2023)

Sanguisorbae Radix Suppresses Colorectal Tumor Growth Through PD-1/PD-L1 Blockade and Synergistic Effect With Pembrolizumab in a Humanized PD-L1-Expressing Colorectal Cancer Mouse Model
por: Lee, Eun-Ji, et al.
Publicado: (2021)

Removal of N-Linked Glycosylation Enhances PD-L1 Detection in Colon Cancer: Validation Research Based on Immunohistochemistry Analysis
por: Xu, Junying, et al.
Publicado: (2021)

PD-L1 regulation by SDH5 via β-catenin/ZEB1 signaling
por: Tuo, Zhan, et al.
Publicado: (2019)

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumor cell PD-L1 expression and intratumoral immunosuppression
por: Chen, Limo, et al.
Publicado: (2014)

MEF2A transcriptionally upregulates the expression of ZEB2 and CTNNB1 in colorectal cancer to promote tumor progression
por: Xiao, Qing, et al.
Publicado: (2021)

Aspirin Suppressed PD-L1 Expression through Suppressing KAT5 and Subsequently Inhibited PD-1 and PD-L1 Signaling to Attenuate OC Development
por: Xiao, Xiyun, et al.
Publicado: (2022)

High expression of ZEB1 correlates with liver metastasis and poor prognosis in colorectal cancer
por: ZHANG, GUANG-JUN, et al.
Publicado: (2013)

Butyrate facilitates immune clearance of colorectal cancer cells by suppressing STAT1-mediated PD-L1 expression
por: Zhang, Yan, et al.
Publicado: (2023)

Expression of Zeb1 in the differentiation of mouse embryonic stem cell
por: Chen, Ting, et al.
Publicado: (2022)

MiR-429 suppresses the progression and metastasis of osteosarcoma by targeting ZEB1
por: Deng, Yi, et al.
Publicado: (2017)

A comparability study of natural and deglycosylated PD-L1 levels in lung cancer: evidence from immunohistochemical analysis
por: Mei, Jie, et al.
Publicado: (2021)

TRIM9 Interacts with ZEB1 to Suppress Esophageal Cancer by Promoting ZEB1 Protein Degradation via the UPP Pathway
por: Lin, Zhaoxian, et al.
Publicado: (2023)

The combination of Biochanin A and SB590885 potentiates the inhibition of tumour progression in hepatocellular carcinoma
por: Xiao, Yi, et al.
Publicado: (2020)

Long noncoding RNA ZEB1-AS1 epigenetically regulates the expressions of ZEB1 and downstream molecules in prostate cancer
por: Su, Wenjing, et al.
Publicado: (2017)

PTEN Loss Increases PD-L1 Protein Expression and Affects the Correlation between PD-L1 Expression and Clinical Parameters in Colorectal Cancer
por: Song, Minmin, et al.
Publicado: (2013)

The Clinical Significance of Deglycosylated PD-L1 Level Detection Using 28-8 Monoclonal Antibody in Lung Adenocarcinoma
por: Wang, Huiyu, et al.
Publicado: (2022)

LncRNA SPRY4-IT1 promotes progression of osteosarcoma by regulating ZEB1 and ZEB2 expression through sponging of miR-101 activity
por: Yao, Hui, et al.
Publicado: (2019)

LINC00894 Enhances the Progression of Breast Cancer by Sponging miR-429 to Regulate ZEB1 Expression
por: Meng, De-feng, et al.
Publicado: (2021)

Characterization of the Clinical Significance of PD-1/PD-Ls Expression and Methylation in Patients With Low-Grade Glioma
por: Mei, Jie, et al.
Publicado: (2021)

Protein tyrosine phosphatase receptor type delta (PTPRD) suppresses the expression of PD-L1 in human hepatocellular carcinoma by down-regulating STAT3
por: Meng, Qiuhua, et al.
Publicado: (2020)

EFFECT OF BIOCHANIN – A AGAINST FILARIAL VECTOR
por: Nagarajan, N.S., et al.
Publicado: (1998)

Perspectives Regarding the Role of Biochanin A in Humans
por: Yu, Chen, et al.
Publicado: (2019)

PD-L1 Expression in Mastocytosis
por: Williams, Margaret, et al.
Publicado: (2019)

PD-L1: expression regulation
por: Zhou, Yu-Jie, et al.
Publicado: (2023)

PHRF1 promotes migration and invasion by modulating ZEB1 expression
por: Lee, Jin-Yu, et al.
Publicado: (2020)

Expression of PD-1, PD-L1 and PD-L2 is associated with differentiation status and histological type of endometrial cancer
por: Mo, Zhongfu, et al.
Publicado: (2016)

Role of regulation of PD-1 and PD-L1 expression in sepsis
por: Zhang, Teng, et al.
Publicado: (2023)

PD-1 and PD-L1 expression in rare lung tumors
por: Gyulai, Marton, et al.
Publicado: (2023)

Current progress and future perspectives of neoadjuvant anti-PD-1/PD-L1 therapy for colorectal cancer
por: Yang, Zhengyang, et al.
Publicado: (2022)

ICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous- Carcinoma Immune Microenvironment
por: Zhang, Yu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cvi4qg78tkeisa2loe4g5ccftd