The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα

Uncontrolled gluconeogenesis results in elevated hepatic glucose production in type 2 diabetes (T2D). The small ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is known to catalyze deSUMOylation of target proteins, with broad effects on cell growth, signal transduction, and development...

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Detalles Bibliográficos
Autores principales: Dou, Xin, Zhou, Wei-Yu, Ding, Meng, Ma, Yin-Jun, Yang, Qi-Qi, Qian, Shu-Wen, Tang, Yan, Tang, Qi-Qun, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888337/
https://www.ncbi.nlm.nih.gov/pubmed/34971706
http://dx.doi.org/10.1016/j.jbc.2021.101544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888337/
https://www.ncbi.nlm.nih.gov/pubmed/34971706
http://dx.doi.org/10.1016/j.jbc.2021.101544

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