Sa12b-Modified Functional Self-Assembling Peptide Hydrogel Enhances the Biological Activity of Nucleus Pulposus Mesenchymal Stem Cells by Inhibiting Acid-Sensing Ion Channels

Various hydrogels have been studied for nucleus pulposus regeneration. However, they failed to overcome the changes in the acidic environment during intervertebral disc degeneration. Therefore, a new functionalized peptide RAD/SA1 was designed by conjugating Sa12b, an inhibitor of acid-sensing ion c...

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Detalles Bibliográficos
Autores principales: Han, Letian, Wang, Ziyu, Chen, Haoyu, Li, Jie, Zhang, Shengquan, Zhang, Sumei, Shao, Shanzhong, Zhang, Yinshun, Shen, Cailiang, Tao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888415/
https://www.ncbi.nlm.nih.gov/pubmed/35252187
http://dx.doi.org/10.3389/fcell.2022.822501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888415/
https://www.ncbi.nlm.nih.gov/pubmed/35252187
http://dx.doi.org/10.3389/fcell.2022.822501

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