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Circulating Memory B Cells in Early Multiple Sclerosis Exhibit Increased IgA(+) Cells, Globally Decreased BAFF-R Expression and an EBV-Related IgM(+) Cell Signature

Multiple sclerosis (MS) is an immune-mediated inflammatory disease of the central nervous system that results in demyelination of axons, inefficient signal transmission and reduced muscular mobility. Recent findings suggest that B cells play a significant role in disease development and pathology. T...

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Detalles Bibliográficos
Autores principales:	Leffler, Jonatan, Trend, Stephanie, Ward, Natalie C., Grau, Georges E., Hawke, Simon, Byrne, Scott N., Kermode, Allan G., French, Martyn A., Hart, Prue H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888440/ https://www.ncbi.nlm.nih.gov/pubmed/35250986 http://dx.doi.org/10.3389/fimmu.2022.812317

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