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Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment

The human hematopoietic stem cell harbors remarkable regenerative potential that can be harnessed therapeutically. During early development, hematopoietic stem cells in the fetal liver undergo active expansion while simultaneously retaining robust engraftment capacity, yet the underlying molecular p...

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Detalles Bibliográficos
Autores principales: Vanuytsel, Kim, Villacorta-Martin, Carlos, Lindstrom-Vautrin, Jonathan, Wang, Zhe, Garcia-Beltran, Wilfredo F., Vrbanac, Vladimir, Parsons, Dylan, Lam, Evan C., Matte, Taylor M., Dowrey, Todd W., Kumar, Sara S., Li, Mengze, Wang, Feiya, Yeung, Anthony K., Mostoslavsky, Gustavo, Dries, Ruben, Campbell, Joshua D., Belkina, Anna C., Balazs, Alejandro B., Murphy, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888592/
https://www.ncbi.nlm.nih.gov/pubmed/35232959
http://dx.doi.org/10.1038/s41467-022-28616-x

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