H5N1 infection impairs the alveolar epithelial barrier through intercellular junction proteins via Itch-mediated proteasomal degradation

The H5N1 subtype of the avian influenza virus causes sporadic but fatal infections in humans. H5N1 virus infection leads to the disruption of the alveolar epithelial barrier, a pathologic change that often progresses into acute respiratory distress syndrome (ARDS) and pneumonia. The mechanisms under...

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Detalles Bibliográficos
Autores principales: Ruan, Tao, Sun, Yuling, Zhang, Jingting, Sun, Jing, Liu, Wei, Prinz, Richard A., Peng, Daxin, Liu, Xiufan, Xu, Xiulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888635/
https://www.ncbi.nlm.nih.gov/pubmed/35233032
http://dx.doi.org/10.1038/s42003-022-03131-3

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