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Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity

In the context of HLA-DP-mismatched allogeneic stem cell transplantation, mismatched HLA-DP alleles can provoke profound allo-HLA-DP-specific immune responses from the donor T-cell repertoire leading to graft-versus-leukemia effect and/or graft-versus-host disease in the patient. The magnitude of al...

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Detalles Bibliográficos
Autores principales:	Laghmouchi, Aicha, Kester, Michel G. D., Hoogstraten, Conny, Hageman, Lois, de Klerk, Wendy, Huisman, Wesley, Koster, Eva A. S., de Ru, Arnoud H., van Balen, Peter, Klobuch, Sebastian, van Veelen, Peter A., Falkenburg, J. H. Frederik, Jedema, Inge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888658/ https://www.ncbi.nlm.nih.gov/pubmed/35251023 http://dx.doi.org/10.3389/fimmu.2022.831822

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