Cargando…
The PER1/HIF-1alpha negative feedback loop promotes ferroptosis and inhibits tumor progression in oral squamous cell carcinoma
Current studies have proven that the decreased expression of the core circadian clock gene Period 1 (PER1) is closely related to the occurrence and progression of multiple malignant tumors, including oral squamous cell carcinoma (OSCC). But the mechanism involved is largely unknown. In this study, w...
Autores principales: | Yang, Yixin, Tang, Hong, Zheng, Jiawen, Yang, Kai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888721/ https://www.ncbi.nlm.nih.gov/pubmed/35134674 http://dx.doi.org/10.1016/j.tranon.2022.101360 |
Ejemplares similares
-
Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway
por: Yang, Guojun, et al.
Publicado: (2020) -
FGF2 Translationally Induced by Hypoxia Is Involved in Negative and Positive Feedback Loops with HIF-1α
por: Conte, Caroline, et al.
Publicado: (2008) -
The Per2 Negative Feedback Loop Sets the Period in the Mammalian Circadian Clock Mechanism
por: Wilkins, A. Katharina, et al.
Publicado: (2007) -
The Study of Expression of Hypoxia-Inducible Factor-1 Alpha (HIF-1 Alpha) and Hypoxia-Inducible Factor-2 Alpha (HIF-2 Alpha) in Oral Squamous Cell Carcinoma: An Immunohistochemical Study
por: Mahapatra, Niva, et al.
Publicado: (2023) -
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance
por: Shi, Bin, et al.
Publicado: (2022)