Ferroptosis: A New Strategy for Cancer Therapy

Ferroptosis is a newly discovered form of iron-dependent cell death, which is different from other death forms. The main characteristics of ferroptosis are: (1) Amino acid metabolism. (2) Iron metabolism; (3) Lipid metabolism and Reactive oxygen species (ROS). Ferroptosis is related to the occurrenc...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Fan, Zhihua, Hu, Shen, Lu, Chengchao, Xiang, Yi, Liao, Shuzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888853/
https://www.ncbi.nlm.nih.gov/pubmed/35252001
http://dx.doi.org/10.3389/fonc.2022.830561
Descripción
Sumario:Ferroptosis is a newly discovered form of iron-dependent cell death, which is different from other death forms. The main characteristics of ferroptosis are: (1) Amino acid metabolism. (2) Iron metabolism; (3) Lipid metabolism and Reactive oxygen species (ROS). Ferroptosis is related to the occurrence and development of a variety of cancers, especially in the drug resistance. This article reviews the research progress of iron death in tumors, and provides a theoretical reference for its further research and clinical application.

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