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Compounds enhancing human sperm motility identified using a high-throughput phenotypic screening platform

STUDY QUESTION: Can a high-throughput screening (HTS) platform facilitate male fertility drug discovery? SUMMARY ANSWER: An HTS platform identified a large number of compounds that enhanced sperm motility. WHAT IS KNOWN ALREADY: Several efforts to find small molecules modulating sperm function have...

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Detalles Bibliográficos
Autores principales: Gruber, Franz S, Johnston, Zoe C, Norcross, Neil R, Georgiou, Irene, Wilson, Caroline, Read, Kevin D, Gilbert, Ian H, Swedlow, Jason R, Martins da Silva, Sarah, Barratt, Christopher L R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888995/
https://www.ncbi.nlm.nih.gov/pubmed/35048946
http://dx.doi.org/10.1093/humrep/deac007

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