Reduced Neutrophil Extracellular Trap Formation During Ischemia Reperfusion Injury in C3 KO Mice: C3 Requirement for NETs Release

Complement C3 plays a prominent role in inflammatory processes, and its increase exacerbates ischemia reperfusion injury (IRI)-induced acute kidney injury (AKI). Infiltrated neutrophils can be stimulated to form neutrophil extracellular traps (NETs), leading to renal injury. However, the relationshi...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoting, You, Danyu, Cui, Jiong, Yang, Liyan, Lin, Liyu, Chen, Yi, Xu, Changsheng, Lian, Guili, Wan, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889019/
https://www.ncbi.nlm.nih.gov/pubmed/35250972
http://dx.doi.org/10.3389/fimmu.2022.781273

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