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TMI-1, TNF-α-Converting Enzyme Inhibitor, Protects Against Paclitaxel-Induced Neurotoxicity in the DRG Neuronal Cells In Vitro

Background: Chemotherapy-induced peripheral neuropathy (CIPN) negatively impacts cancer survivors’ quality of life and is challenging to treat with existing drugs for neuropathic pain. TNF-α is known to potentiate TRPV1 activity, which contributes to CIPN. Here, we assessed the role of TMI-1, a TNF-...

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Detalles Bibliográficos
Autores principales:	Kim, Yesul, Jung, Young-Hoon, Park, Seung-Bin, Kim, Heekee, Kwon, Jae-young, Kim, Hae-kyu, Lee, Hyeon-Jeong, Jeon, Soeun, Kim, Eunsoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889072/ https://www.ncbi.nlm.nih.gov/pubmed/35250589 http://dx.doi.org/10.3389/fphar.2022.842779

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