Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2

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Thyroid hormones (THs) are key metabolic regulators coordinating short- and long-term energy needs. In skeletal muscle, THs modulate energy metabolism in pathophysiological conditions. Indeed, hypo- and hyperthyroidism are leading causes of muscle weakness and strength; however, the metabolic pathwa...

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Detalles Bibliográficos
Autores principales: Cicatiello, Annunziata Gaetana, Sagliocchi, Serena, Nappi, Annarita, Di Cicco, Emery, Miro, Caterina, Murolo, Melania, Stornaiuolo, Mariano, Dentice, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889437/
https://www.ncbi.nlm.nih.gov/pubmed/35196498
http://dx.doi.org/10.1016/j.celrep.2022.110409
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