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Comparison of dietary acid load score between celiac patients and healthy population

BACKGROUND AND AIMS: In the present study, we assessed the dietary acid load in adult celiac patients and compared it with that of the healthy population to provide more specific dietary recommendations for celiac patients. METHODS: This study was a cross-sectional study that included 130 celiac pat...

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Autores principales: Nikniaz, Zeinab, Mahdavi, Reza, Akhavan Sabbagh, Mojgan, Nikniaz, Leila, Shirmohammadi, Masood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889752/
https://www.ncbi.nlm.nih.gov/pubmed/35232484
http://dx.doi.org/10.1186/s40795-022-00512-z
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author Nikniaz, Zeinab
Mahdavi, Reza
Akhavan Sabbagh, Mojgan
Nikniaz, Leila
Shirmohammadi, Masood
author_facet Nikniaz, Zeinab
Mahdavi, Reza
Akhavan Sabbagh, Mojgan
Nikniaz, Leila
Shirmohammadi, Masood
author_sort Nikniaz, Zeinab
collection PubMed
description BACKGROUND AND AIMS: In the present study, we assessed the dietary acid load in adult celiac patients and compared it with that of the healthy population to provide more specific dietary recommendations for celiac patients. METHODS: This study was a cross-sectional study that included 130 celiac patients and 462 Non-celiac participants. The 80-item semi-quantitative food frequency questionnaire was used to obtain dietary data. Based on the dietary data, the dietary acid load (DAL), Potential renal net acid load (PRAL), and net endogenous acid production (NEAP) were calculated. RESULTS: The mean PRAL value is negative in the celiac group but positive in the general population. There was a significant difference in the PRAL score between celiac patients and the general population (p < 0.001). The mean NEAP and DAL score were significantly lower in the celiac group compared with the healthy population (P < 0.001). There were no significant differences between gluten-free diet adherents and non-adherents regarding the PRAL, NEAP, and DAL values (P > 0.05). CONCLUSION: We showed that the patients with celiac disease had a significantly less acidogenic diet compared with that of the general population. So, following dies low in gluten may be associated with less acid production spacially in populations at risk of acid/base imbalance.
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spelling pubmed-88897522022-03-09 Comparison of dietary acid load score between celiac patients and healthy population Nikniaz, Zeinab Mahdavi, Reza Akhavan Sabbagh, Mojgan Nikniaz, Leila Shirmohammadi, Masood BMC Nutr Research BACKGROUND AND AIMS: In the present study, we assessed the dietary acid load in adult celiac patients and compared it with that of the healthy population to provide more specific dietary recommendations for celiac patients. METHODS: This study was a cross-sectional study that included 130 celiac patients and 462 Non-celiac participants. The 80-item semi-quantitative food frequency questionnaire was used to obtain dietary data. Based on the dietary data, the dietary acid load (DAL), Potential renal net acid load (PRAL), and net endogenous acid production (NEAP) were calculated. RESULTS: The mean PRAL value is negative in the celiac group but positive in the general population. There was a significant difference in the PRAL score between celiac patients and the general population (p < 0.001). The mean NEAP and DAL score were significantly lower in the celiac group compared with the healthy population (P < 0.001). There were no significant differences between gluten-free diet adherents and non-adherents regarding the PRAL, NEAP, and DAL values (P > 0.05). CONCLUSION: We showed that the patients with celiac disease had a significantly less acidogenic diet compared with that of the general population. So, following dies low in gluten may be associated with less acid production spacially in populations at risk of acid/base imbalance. BioMed Central 2022-03-01 /pmc/articles/PMC8889752/ /pubmed/35232484 http://dx.doi.org/10.1186/s40795-022-00512-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Nikniaz, Zeinab
Mahdavi, Reza
Akhavan Sabbagh, Mojgan
Nikniaz, Leila
Shirmohammadi, Masood
Comparison of dietary acid load score between celiac patients and healthy population
title Comparison of dietary acid load score between celiac patients and healthy population
title_full Comparison of dietary acid load score between celiac patients and healthy population
title_fullStr Comparison of dietary acid load score between celiac patients and healthy population
title_full_unstemmed Comparison of dietary acid load score between celiac patients and healthy population
title_short Comparison of dietary acid load score between celiac patients and healthy population
title_sort comparison of dietary acid load score between celiac patients and healthy population
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889752/
https://www.ncbi.nlm.nih.gov/pubmed/35232484
http://dx.doi.org/10.1186/s40795-022-00512-z
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