Epitope Spreading and the Efficacy of Immune Checkpoint Inhibition in Cancer

Therapeutic antibodies that target immune checkpoints have revolutionized cancer therapy. While these checkpoints restrain T cell activation in response to antigen engagement, checkpoint inhibitors de-repress such tumor-associated T cells, and have generated major clinical responses in multiple tumo...

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Detalles Bibliográficos
Autores principales: Liu, W. Robert, Fisher, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889787/
https://www.ncbi.nlm.nih.gov/pubmed/35243349
http://dx.doi.org/10.23937/2643-4563/1710029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889787/
https://www.ncbi.nlm.nih.gov/pubmed/35243349
http://dx.doi.org/10.23937/2643-4563/1710029

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