Cargando…

Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review

Patients with gastric cancer are often malnourished or sarcopenic during tumor progression. Perioperative malnutrition, including sarcopenia, is strongly related to postoperative complications and long‐term outcomes. To improve outcomes, nutritional intervention is common for patients with gastric c...

Descripción completa

Detalles Bibliográficos
Autores principales: Ida, Satoshi, Kumagai, Koshi, Nunobe, Souya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889851/
https://www.ncbi.nlm.nih.gov/pubmed/35261945
http://dx.doi.org/10.1002/ags3.12520
_version_ 1784661503549374464
author Ida, Satoshi
Kumagai, Koshi
Nunobe, Souya
author_facet Ida, Satoshi
Kumagai, Koshi
Nunobe, Souya
author_sort Ida, Satoshi
collection PubMed
description Patients with gastric cancer are often malnourished or sarcopenic during tumor progression. Perioperative malnutrition, including sarcopenia, is strongly related to postoperative complications and long‐term outcomes. To improve outcomes, nutritional intervention is common for patients with gastric cancer, especially for those undergoing elective surgery. Several clinical trials evaluating perioperative nutritional intervention have set postoperative loss of body weight and lean body mass as endpoints; however, the results were inconsistent. Therefore, recently, perioperative multimodal interventions that are expected to have a synergistic effect between nutritional intervention and exercise have gained attention. Furthermore, supplementing with leucine, a branched‐chain amino acid, in addition to exercise, may be promising for preventing perioperative sarcopenia. However, whether perioperative nutritional intervention and exercise has clinical benefits in gastric surgery is unclear. With the aging of gastric cancer patients, measures to address sarcopenia will become more important in the future. Understanding the significance of nutritional intervention and exercise in patients undergoing gastric cancer surgery will help achieve good outcomes.
format Online
Article
Text
id pubmed-8889851
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-88898512022-03-07 Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review Ida, Satoshi Kumagai, Koshi Nunobe, Souya Ann Gastroenterol Surg Review Articles Patients with gastric cancer are often malnourished or sarcopenic during tumor progression. Perioperative malnutrition, including sarcopenia, is strongly related to postoperative complications and long‐term outcomes. To improve outcomes, nutritional intervention is common for patients with gastric cancer, especially for those undergoing elective surgery. Several clinical trials evaluating perioperative nutritional intervention have set postoperative loss of body weight and lean body mass as endpoints; however, the results were inconsistent. Therefore, recently, perioperative multimodal interventions that are expected to have a synergistic effect between nutritional intervention and exercise have gained attention. Furthermore, supplementing with leucine, a branched‐chain amino acid, in addition to exercise, may be promising for preventing perioperative sarcopenia. However, whether perioperative nutritional intervention and exercise has clinical benefits in gastric surgery is unclear. With the aging of gastric cancer patients, measures to address sarcopenia will become more important in the future. Understanding the significance of nutritional intervention and exercise in patients undergoing gastric cancer surgery will help achieve good outcomes. John Wiley and Sons Inc. 2021-10-26 /pmc/articles/PMC8889851/ /pubmed/35261945 http://dx.doi.org/10.1002/ags3.12520 Text en © 2021 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review Articles
Ida, Satoshi
Kumagai, Koshi
Nunobe, Souya
Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review
title Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review
title_full Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review
title_fullStr Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review
title_full_unstemmed Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review
title_short Current status of perioperative nutritional intervention and exercise in gastric cancer surgery: A review
title_sort current status of perioperative nutritional intervention and exercise in gastric cancer surgery: a review
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889851/
https://www.ncbi.nlm.nih.gov/pubmed/35261945
http://dx.doi.org/10.1002/ags3.12520
work_keys_str_mv AT idasatoshi currentstatusofperioperativenutritionalinterventionandexerciseingastriccancersurgeryareview
AT kumagaikoshi currentstatusofperioperativenutritionalinterventionandexerciseingastriccancersurgeryareview
AT nunobesouya currentstatusofperioperativenutritionalinterventionandexerciseingastriccancersurgeryareview