Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms

The world is grappling with an unprecedented public health crisis COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates and socioeconomic impacts of the COVID-19, its control is crucial. In the absence of specific treatment, vaccines represent the...

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Autores principales: Jafari, Ameneh, Danesh Pouya, Fahima, Niknam, Zahra, Abdollahpour‑Alitappeh, Meghdad, Rezaei-Tavirani, Mostafa, Rasmi, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890022/
https://www.ncbi.nlm.nih.gov/pubmed/35235159
http://dx.doi.org/10.1007/s11033-022-07132-7
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author Jafari, Ameneh
Danesh Pouya, Fahima
Niknam, Zahra
Abdollahpour‑Alitappeh, Meghdad
Rezaei-Tavirani, Mostafa
Rasmi, Yousef
author_facet Jafari, Ameneh
Danesh Pouya, Fahima
Niknam, Zahra
Abdollahpour‑Alitappeh, Meghdad
Rezaei-Tavirani, Mostafa
Rasmi, Yousef
author_sort Jafari, Ameneh
collection PubMed
description The world is grappling with an unprecedented public health crisis COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates and socioeconomic impacts of the COVID-19, its control is crucial. In the absence of specific treatment, vaccines represent the most efficient way to control and stop the pandemic. Many companies around the world are currently making efforts to develop the vaccine to combat COVID-19. This review outlines key strategies for generating SARS-CoV-2 vaccine candidates, along with the mechanism of action, advantages, and potential limitations of each vaccine. The use of nanomaterials and nanotechnology for COVID-19 vaccines development will also be discussed.
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spelling pubmed-88900222022-03-04 Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms Jafari, Ameneh Danesh Pouya, Fahima Niknam, Zahra Abdollahpour‑Alitappeh, Meghdad Rezaei-Tavirani, Mostafa Rasmi, Yousef Mol Biol Rep Review The world is grappling with an unprecedented public health crisis COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates and socioeconomic impacts of the COVID-19, its control is crucial. In the absence of specific treatment, vaccines represent the most efficient way to control and stop the pandemic. Many companies around the world are currently making efforts to develop the vaccine to combat COVID-19. This review outlines key strategies for generating SARS-CoV-2 vaccine candidates, along with the mechanism of action, advantages, and potential limitations of each vaccine. The use of nanomaterials and nanotechnology for COVID-19 vaccines development will also be discussed. Springer Netherlands 2022-03-02 2022 /pmc/articles/PMC8890022/ /pubmed/35235159 http://dx.doi.org/10.1007/s11033-022-07132-7 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Jafari, Ameneh
Danesh Pouya, Fahima
Niknam, Zahra
Abdollahpour‑Alitappeh, Meghdad
Rezaei-Tavirani, Mostafa
Rasmi, Yousef
Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
title Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
title_full Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
title_fullStr Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
title_full_unstemmed Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
title_short Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
title_sort current advances and challenges in covid-19 vaccine development: from conventional vaccines to next-generation vaccine platforms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890022/
https://www.ncbi.nlm.nih.gov/pubmed/35235159
http://dx.doi.org/10.1007/s11033-022-07132-7
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