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Computational simulations of identified marine-derived natural bioactive compounds as potential inhibitors of oral cancer

Oral squamous cell carcinoma is characterized by the upregulation of RAC-alpha serine/threonine-protein kinase (Akt1) and RAC-beta serine/threonine-protein kinase (Akt2). In this work, Akt1 and Akt2 were inhibited using a cocktail of 20 marine algae chemicals. From the PyRx Virtual Screening Tool, d...

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Detalles Bibliográficos
Autores principales: Natarajan, Prabhu Manickam, Umapathy, Vidhya Rekha, Murali, Anita, Swamikannu, Bhuminathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890117/
https://www.ncbi.nlm.nih.gov/pubmed/35251696
http://dx.doi.org/10.2144/fsoa-2021-0148

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