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Computational simulations of identified marine-derived natural bioactive compounds as potential inhibitors of oral cancer
Oral squamous cell carcinoma is characterized by the upregulation of RAC-alpha serine/threonine-protein kinase (Akt1) and RAC-beta serine/threonine-protein kinase (Akt2). In this work, Akt1 and Akt2 were inhibited using a cocktail of 20 marine algae chemicals. From the PyRx Virtual Screening Tool, d...
Autores principales: | Natarajan, Prabhu Manickam, Umapathy, Vidhya Rekha, Murali, Anita, Swamikannu, Bhuminathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Science Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890117/ https://www.ncbi.nlm.nih.gov/pubmed/35251696 http://dx.doi.org/10.2144/fsoa-2021-0148 |
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