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Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes
We have recently reported a correlation between the accumulation of specific T > C and T > G mutations and the chromosomal instability in cells of Barrett's esophagus (BE), which represents a premalignant condition of esophageal adenocarcinoma. Additionally, we identified seven marker gen...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890392/ https://www.ncbi.nlm.nih.gov/pubmed/35252552 http://dx.doi.org/10.1080/23723556.2022.2026559 |
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author | Busslinger, Georg A. |
author_facet | Busslinger, Georg A. |
author_sort | Busslinger, Georg A. |
collection | PubMed |
description | We have recently reported a correlation between the accumulation of specific T > C and T > G mutations and the chromosomal instability in cells of Barrett's esophagus (BE), which represents a premalignant condition of esophageal adenocarcinoma. Additionally, we identified seven marker genes that facilitate the distinction of individual BE stages by histopathological examination. |
format | Online Article Text |
id | pubmed-8890392 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-88903922022-03-03 Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes Busslinger, Georg A. Mol Cell Oncol Author’s Views We have recently reported a correlation between the accumulation of specific T > C and T > G mutations and the chromosomal instability in cells of Barrett's esophagus (BE), which represents a premalignant condition of esophageal adenocarcinoma. Additionally, we identified seven marker genes that facilitate the distinction of individual BE stages by histopathological examination. Taylor & Francis 2022-01-22 /pmc/articles/PMC8890392/ /pubmed/35252552 http://dx.doi.org/10.1080/23723556.2022.2026559 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Author’s Views Busslinger, Georg A. Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes |
title | Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes |
title_full | Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes |
title_fullStr | Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes |
title_full_unstemmed | Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes |
title_short | Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes |
title_sort | barrett's esophagus stages: their correlation with sbs17-associated dna mutations and the identification of histological marker genes |
topic | Author’s Views |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890392/ https://www.ncbi.nlm.nih.gov/pubmed/35252552 http://dx.doi.org/10.1080/23723556.2022.2026559 |
work_keys_str_mv | AT busslingergeorga barrettsesophagusstagestheircorrelationwithsbs17associateddnamutationsandtheidentificationofhistologicalmarkergenes |