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Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infection

Clostridioides difficile is a major nosocomial pathogen that can cause severe, toxin-mediated diarrhea and pseudomembranous colitis. Recent work has shown that C. difficile exhibits heterogeneity in swimming motility and toxin production in vitro through phase variation by site-specific DNA recombin...

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Detalles Bibliográficos
Autores principales:	Trzilova, Dominika, Warren, Mercedes A. H., Gadda, Nicole C., Williams, Caitlin L., Tamayo, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890394/ https://www.ncbi.nlm.nih.gov/pubmed/35192433 http://dx.doi.org/10.1080/19490976.2022.2038854

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