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Targeting coagulation to unlock antitumor immunity?
Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulatio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890431/ https://www.ncbi.nlm.nih.gov/pubmed/35251772 http://dx.doi.org/10.1080/2162402X.2022.2045696 |
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author | Galmiche, Antoine Saidak, Zuzana Ghiringhelli, François |
author_facet | Galmiche, Antoine Saidak, Zuzana Ghiringhelli, François |
author_sort | Galmiche, Antoine |
collection | PubMed |
description | Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation. |
format | Online Article Text |
id | pubmed-8890431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-88904312022-03-03 Targeting coagulation to unlock antitumor immunity? Galmiche, Antoine Saidak, Zuzana Ghiringhelli, François Oncoimmunology Author’s View Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation. Taylor & Francis 2022-02-24 /pmc/articles/PMC8890431/ /pubmed/35251772 http://dx.doi.org/10.1080/2162402X.2022.2045696 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Author’s View Galmiche, Antoine Saidak, Zuzana Ghiringhelli, François Targeting coagulation to unlock antitumor immunity? |
title | Targeting coagulation to unlock antitumor immunity? |
title_full | Targeting coagulation to unlock antitumor immunity? |
title_fullStr | Targeting coagulation to unlock antitumor immunity? |
title_full_unstemmed | Targeting coagulation to unlock antitumor immunity? |
title_short | Targeting coagulation to unlock antitumor immunity? |
title_sort | targeting coagulation to unlock antitumor immunity? |
topic | Author’s View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890431/ https://www.ncbi.nlm.nih.gov/pubmed/35251772 http://dx.doi.org/10.1080/2162402X.2022.2045696 |
work_keys_str_mv | AT galmicheantoine targetingcoagulationtounlockantitumorimmunity AT saidakzuzana targetingcoagulationtounlockantitumorimmunity AT ghiringhellifrancois targetingcoagulationtounlockantitumorimmunity |