Targeting coagulation to unlock antitumor immunity?

Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulatio...

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Detalles Bibliográficos
Autores principales: Galmiche, Antoine, Saidak, Zuzana, Ghiringhelli, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Author’s View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890431/
https://www.ncbi.nlm.nih.gov/pubmed/35251772
http://dx.doi.org/10.1080/2162402X.2022.2045696
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author Galmiche, Antoine
Saidak, Zuzana
Ghiringhelli, François
author_facet Galmiche, Antoine
Saidak, Zuzana
Ghiringhelli, François
author_sort Galmiche, Antoine
collection PubMed
description Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation.
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spelling pubmed-88904312022-03-03 Targeting coagulation to unlock antitumor immunity? Galmiche, Antoine Saidak, Zuzana Ghiringhelli, François Oncoimmunology Author’s View Besides a number of physical consequences (reduced blood supply, stabilization of circulating tumor microemboli, shielding from the attack of immune cells), the coagulation cascade may specifically regulate antitumor immunity. We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation. Taylor & Francis 2022-02-24 /pmc/articles/PMC8890431/ /pubmed/35251772 http://dx.doi.org/10.1080/2162402X.2022.2045696 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Author’s View
Galmiche, Antoine
Saidak, Zuzana
Ghiringhelli, François
Targeting coagulation to unlock antitumor immunity?
title Targeting coagulation to unlock antitumor immunity?
title_full Targeting coagulation to unlock antitumor immunity?
title_fullStr Targeting coagulation to unlock antitumor immunity?
title_full_unstemmed Targeting coagulation to unlock antitumor immunity?
title_short Targeting coagulation to unlock antitumor immunity?
title_sort targeting coagulation to unlock antitumor immunity?
topic Author’s View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890431/
https://www.ncbi.nlm.nih.gov/pubmed/35251772
http://dx.doi.org/10.1080/2162402X.2022.2045696
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