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Sex Differences in Susceptibility to Coccidioidomycosis

To assess sex-specific differences in coccidioidomycosis, a retrospective analysis of human patients, nonhuman primates, and veterinary patients (including the neutered status of the animal) was performed. We found higher rates of infection and severity in males. This observed increased infection ri...

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Autores principales: McHardy, Ian, Reagan, Krystle L, Sebastian, Jamie F, Barker, Bridget, Bays, Derek J, Dandekar, Satya, Cohen, Stuart H, Jennings, Kathleen E, Sykes, Jane, Thompson, George R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890500/
https://www.ncbi.nlm.nih.gov/pubmed/35252466
http://dx.doi.org/10.1093/ofid/ofab543
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author McHardy, Ian
Reagan, Krystle L
Sebastian, Jamie F
Barker, Bridget
Bays, Derek J
Dandekar, Satya
Cohen, Stuart H
Jennings, Kathleen E
Sykes, Jane
Thompson, George R
author_facet McHardy, Ian
Reagan, Krystle L
Sebastian, Jamie F
Barker, Bridget
Bays, Derek J
Dandekar, Satya
Cohen, Stuart H
Jennings, Kathleen E
Sykes, Jane
Thompson, George R
author_sort McHardy, Ian
collection PubMed
description To assess sex-specific differences in coccidioidomycosis, a retrospective analysis of human patients, nonhuman primates, and veterinary patients (including the neutered status of the animal) was performed. We found higher rates of infection and severity in males. This observed increased infection risk suggests deeper biological underpinnings than solely occupational/exposure risks.
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spelling pubmed-88905002022-03-03 Sex Differences in Susceptibility to Coccidioidomycosis McHardy, Ian Reagan, Krystle L Sebastian, Jamie F Barker, Bridget Bays, Derek J Dandekar, Satya Cohen, Stuart H Jennings, Kathleen E Sykes, Jane Thompson, George R Open Forum Infect Dis Brief Report To assess sex-specific differences in coccidioidomycosis, a retrospective analysis of human patients, nonhuman primates, and veterinary patients (including the neutered status of the animal) was performed. We found higher rates of infection and severity in males. This observed increased infection risk suggests deeper biological underpinnings than solely occupational/exposure risks. Oxford University Press 2022-02-16 /pmc/articles/PMC8890500/ /pubmed/35252466 http://dx.doi.org/10.1093/ofid/ofab543 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
McHardy, Ian
Reagan, Krystle L
Sebastian, Jamie F
Barker, Bridget
Bays, Derek J
Dandekar, Satya
Cohen, Stuart H
Jennings, Kathleen E
Sykes, Jane
Thompson, George R
Sex Differences in Susceptibility to Coccidioidomycosis
title Sex Differences in Susceptibility to Coccidioidomycosis
title_full Sex Differences in Susceptibility to Coccidioidomycosis
title_fullStr Sex Differences in Susceptibility to Coccidioidomycosis
title_full_unstemmed Sex Differences in Susceptibility to Coccidioidomycosis
title_short Sex Differences in Susceptibility to Coccidioidomycosis
title_sort sex differences in susceptibility to coccidioidomycosis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890500/
https://www.ncbi.nlm.nih.gov/pubmed/35252466
http://dx.doi.org/10.1093/ofid/ofab543
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