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On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic

High quality daily testing for the presence of the SARS-CoV-2 in workplace settings has become part of the standard and mandatory protection measures implemented widely in response to the current pandemic. Such tests are often limited to a small fraction of the attending personnel due to cost consid...

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Detalles Bibliográficos
Autores principales: Hernandez, X., Valentinotti, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890654/
https://www.ncbi.nlm.nih.gov/pubmed/35235566
http://dx.doi.org/10.1371/journal.pone.0264060
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author Hernandez, X.
Valentinotti, S.
author_facet Hernandez, X.
Valentinotti, S.
author_sort Hernandez, X.
collection PubMed
description High quality daily testing for the presence of the SARS-CoV-2 in workplace settings has become part of the standard and mandatory protection measures implemented widely in response to the current pandemic. Such tests are often limited to a small fraction of the attending personnel due to cost considerations, limited availability and processing capabilities and the often cumbersome requirements of the test itself. A maximally efficient use of such an important and frequently scarce resource is clearly required. We here present an optimal testing strategy which minimises the presence of pre-symptomatic and asymptomatic infected members of the population in a workplace setting, derived under a series of simplifying statistical assumptions. These assumptions however, retain many of the generalities of the problem and yield robust results, as verified through a number of numerical simulations. We show that reduction in overall infected-person-days, IPD, by significant percentages can be achieved, for fixed numbers of tests per day of 5% and 10% of the population, of 30% and 50% in the IPD numbers, respectively.
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spelling pubmed-88906542022-03-03 On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic Hernandez, X. Valentinotti, S. PLoS One Research Article High quality daily testing for the presence of the SARS-CoV-2 in workplace settings has become part of the standard and mandatory protection measures implemented widely in response to the current pandemic. Such tests are often limited to a small fraction of the attending personnel due to cost considerations, limited availability and processing capabilities and the often cumbersome requirements of the test itself. A maximally efficient use of such an important and frequently scarce resource is clearly required. We here present an optimal testing strategy which minimises the presence of pre-symptomatic and asymptomatic infected members of the population in a workplace setting, derived under a series of simplifying statistical assumptions. These assumptions however, retain many of the generalities of the problem and yield robust results, as verified through a number of numerical simulations. We show that reduction in overall infected-person-days, IPD, by significant percentages can be achieved, for fixed numbers of tests per day of 5% and 10% of the population, of 30% and 50% in the IPD numbers, respectively. Public Library of Science 2022-03-02 /pmc/articles/PMC8890654/ /pubmed/35235566 http://dx.doi.org/10.1371/journal.pone.0264060 Text en © 2022 Hernandez, Valentinotti https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Hernandez, X.
Valentinotti, S.
On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
title On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
title_full On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
title_fullStr On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
title_full_unstemmed On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
title_short On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
title_sort on an optimal testing strategy for workplace settings operating during the covid-19 pandemic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890654/
https://www.ncbi.nlm.nih.gov/pubmed/35235566
http://dx.doi.org/10.1371/journal.pone.0264060
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