Premature aging in mice with error-prone protein synthesis

The main source of error in gene expression is messenger RNA decoding by the ribosome. Translational accuracy has been suggested on a purely correlative basis to positively coincide with maximum possible life span among different rodent species, but causal evidence that translation errors accelerate...

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Detalles Bibliográficos
Autores principales: Shcherbakov, Dimitri, Nigri, Martina, Akbergenov, Rashid, Brilkova, Margarita, Mantovani, Matilde, Petit, Patricia Isnard, Grimm, Amandine, Karol, Agnieszka A., Teo, Youjin, Sanchón, Adrián Cortés, Kumar, Yadhu, Eckert, Anne, Thiam, Kader, Seebeck, Petra, Wolfer, David P., Böttger, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890705/
https://www.ncbi.nlm.nih.gov/pubmed/35235349
http://dx.doi.org/10.1126/sciadv.abl9051

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