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Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors

Proinflammatory cytokines have been approved by the Food and Drug Administration for the treatment of metastatic melanoma and renal carcinoma. However, effective cytokine therapy requires high-dose infusions that can result in antidrug antibodies and/or systemic side effects that limit long-term ben...

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Detalles Bibliográficos
Autores principales: Nash, Amanda M., Jarvis, Maria I., Aghlara-Fotovat, Samira, Mukherjee, Sudip, Hernandez, Andrea, Hecht, Andrew D., Rios, Peter D., Ghani, Sofia, Joshi, Ira, Isa, Douglas, Cui, Yufei, Nouraein, Shirin, Lee, Jared Z., Xu, Chunyu, Zhang, David Y., Sheth, Rahul A., Peng, Weiyi, Oberholzer, Jose, Igoshin, Oleg A., Jazaeri, Amir A., Veiseh, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890714/
https://www.ncbi.nlm.nih.gov/pubmed/35235346
http://dx.doi.org/10.1126/sciadv.abm1032