Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms

The involvement of genetic risk and the underlying developmental and neural circuit mechanisms in autism-related social deficit are largely unclear. Here, we report that deletion of AUTS2, a high-susceptibility gene of ASDs, caused postnatal dentate gyrus (DG) hypoplasia, which was closely relevant...

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Detalles Bibliográficos
Autores principales: Li, Jun, Sun, Xiaoxuan, You, Yang, Li, Qiongwei, Wei, Chengwen, Zhao, Linnan, Sun, Mengwen, Meng, Hu, Zhang, Tian, Yue, Weihua, Wang, Lifang, Zhang, Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890717/
https://www.ncbi.nlm.nih.gov/pubmed/35235353
http://dx.doi.org/10.1126/sciadv.abk1238

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