Cargando…

Safety and Pharmacokinetics of Intranasally Administered Heparin

Mostrar otras versiones (1)

PURPOSE: Intranasally administered unfractionated heparin (UFH) and other sulfated polysaccharides are potential prophylactics for COVID-19. The purpose of this research was to measure the safety and pharmacokinetics of clearance of intranasally administered UFH solution from the nasal cavity. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harris, Hannah M., Boyet, Katherine L., Liu, Hao, Dwivedi, Rohini, Ashpole, Nicole M., Tandon, Ritesh, Bidwell, Gene L., Cheng, Zhi, Fassero, Lauren A., Yu, Christian S., Pomin, Vitor H., Mitra, Dipanwita, Harrison, Kerri A., Dahl, Eric, Gurley, Bill J., Kotha, Arun Kumar, Chougule, Mahavir Bhupal, Sharp, Joshua S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890767/ https://www.ncbi.nlm.nih.gov/pubmed/35237922 http://dx.doi.org/10.1007/s11095-022-03191-4

Ejemplares similares

Safety and Pharmacokinetics of Intranasally Administered Heparin
por: Harris, Hannah M., et al.
Publicado: (2022)

Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
por: Tandon, Ritesh, et al.
Publicado: (2020)

Inhibition of SARS-CoV-2 wild-type (Wuhan-Hu-1) and Delta (B.1.617.2) strains by marine sulfated glycans
por: Dwivedi, Rohini, et al.
Publicado: (2022)

Inhibition of Cytomegalovirus by Pentacta pygmaea Fucosylated Chondroitin Sulfate Depends on Its Molecular Weight
por: Sharma, Poonam, et al.
Publicado: (2023)

Structural requirements of Holothuria floridana fucosylated chondroitin sulfate oligosaccharides in anti-SARS-CoV-2 and anticoagulant activities
por: Farrag, Marwa, et al.
Publicado: (2023)

Tegument Protein pp150 Sequence-Specific Peptide Blocks Cytomegalovirus Infection
por: Mitra, Dipanwita, et al.
Publicado: (2021)

Marine Antithrombotics
por: Dwivedi, Rohini, et al.
Publicado: (2020)

Pharmacokinetics of Intranasally Administered Dexmedetomidine in Chinese Children
por: Wang, Cheng-Yu, et al.
Publicado: (2019)

Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system
por: McGowan, Jeremy WD, et al.
Publicado: (2016)

The rapid diagnosis and effective inhibition of coronavirus using spike antibody attached gold nanoparticles
por: Pramanik, Avijit, et al.
Publicado: (2021)

Observational study of administering intranasal steroid sprays by healthcare workers
por: de Boer, Marielle, et al.
Publicado: (2020)

(1)H and (15)N NMR Analyses on Heparin, Heparan Sulfates and Related Monosaccharides Concerning the Chemical Exchange Regime of the N-Sulfo-Glucosamine Sulfamate Proton
por: Pomin, Vitor H.
Publicado: (2016)

Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection
por: Dwivedi, Rohini, et al.
Publicado: (2021)

Benefit, Necessity or Harm by Administering Heparin during Neurointerventional Procedures?
por: Berlis, Ansgar
Publicado: (2021)

Preparation, characterization, and in vivo evaluation of intranasally administered liposomal formulation of donepezil
por: Al Asmari, Abdulrahman K, et al.
Publicado: (2016)

The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells
por: Mitra, Dipanwita, et al.
Publicado: (2021)

Antiviral activity of marine sulfated glycans against pathogenic human coronaviruses
por: Zoepfl, Mary, et al.
Publicado: (2023)

Intranasally Administered Adjunctive Dexmedetomidine Reduces Perioperative Anesthetic Requirements in General Anesthesia
por: Wu, Xiang, et al.
Publicado: (2016)

Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally
por: Howe, Savannah E., et al.
Publicado: (2016)

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques
por: Lee, M. R., et al.
Publicado: (2020)

Pharmacokinetics and pharmacodynamics of intranasal and intramuscular administration of naloxone in working dogs administered fentanyl
por: Barr, Ciara A., et al.
Publicado: (2023)

Nano-liposomal dry powder inhaler of tacrolimus: Preparation, characterization, and pulmonary pharmacokinetics
por: Chougule, Mahavir, et al.
Publicado: (2007)

Formulation Development and Evaluation of Hybrid Nanocarrier for Cancer Therapy: Taguchi Orthogonal Array Based Design
por: Tekade, Rakesh K., et al.
Publicado: (2013)

Enhanced Anticancer Activity of PF-04691502, a Dual PI3K/mTOR Inhibitor, in Combination With VEGF siRNA Against Non–small-cell Lung Cancer
por: Espana-Serrano, Laura, et al.
Publicado: (2016)

Heparin Administered to Anopheles in Membrane Feeding Assays Blocks Plasmodium Development in the Mosquito
por: Lantero, Elena, et al.
Publicado: (2020)

In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine
por: Vilekar, Prachi, et al.
Publicado: (2010)

Intranasally Administered MSC-Derived Extracellular Vesicles Reverse Cisplatin-Induced Cognitive Impairment
por: Milutinovic, Bojana, et al.
Publicado: (2023)

COUNTERPOINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No
por: Jimenez, David, et al.
Publicado: (2022)

Enhancing Patient Choice: Using Self-administered Intranasal Naloxone for Novel Rapid Buprenorphine Initiation
por: Randall, Adam, et al.
Publicado: (2023)

An Experience of Multiple Hematomas in a Coronavirus Disease-19 Patient Administered with ART-123 and Heparin
por: Shiraki, Hideto, et al.
Publicado: (2021)

POINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? Yes
por: Tritschler, Tobias, et al.
Publicado: (2022)

Comparison of medication acceptance of intranasal midazolam administered by parents versus doctors in children – A randomized trial
por: Prakash, M. V. S. Satya, et al.
Publicado: (2020)

Using the Intranasal Route to Administer Drugs to Treat Neurological and Psychiatric Illnesses: Rationale, Successes, and Future Needs
por: Lofts, Andrew, et al.
Publicado: (2022)

Antitumor Activity of Noscapine in Combination with Doxorubicin in Triple Negative Breast Cancer
por: Chougule, Mahavir B., et al.
Publicado: (2011)

Effect of intranasally administered insulin on cerebral blood flow and perfusion; a randomized experiment in young and older adults
por: Akintola, Abimbola A., et al.
Publicado: (2017)

Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to Mycobacterium tuberculosis infection
por: Kieswetter, Nathan S., et al.
Publicado: (2022)

Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1
por: Mishra, Gaurav, et al.
Publicado: (2022)

Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice
por: Cotter, Catherine A., et al.
Publicado: (2023)

Enhanced Anticancer Activity of Gemcitabine in Combination with Noscapine via Antiangiogenic and Apoptotic Pathway against Non-Small Cell Lung Cancer
por: Chougule, Mahavir B., et al.
Publicado: (2011)

Intranasally administered in situ gelling nanocomposite system of dimenhydrinate: preparation, characterization and pharmacodynamic applicability in chemotherapy induced emesis model
por: Barakat, Sara S., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0uc35ore61e0hqulu9nq260rku