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miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway

BACKGROUND: Glaucoma is characterized by elevated intraocular pressure caused by aqueous outflow dysfunction. Trabecular meshwork plays a key role in controlling intraocular pressure by modulating aqueous outflow. This study investigated the protective effects of miR-486-5p in H(2)O(2)-stimulated hu...

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Detalles Bibliográficos
Autores principales:	Xu, Le, Zhang, Yiming, Long, Hua, Zhou, Bo, Jiang, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890899/ https://www.ncbi.nlm.nih.gov/pubmed/35251709 http://dx.doi.org/10.1155/2022/3584192

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