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Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection
Background The majority of patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection present mild symptoms. However, some patients develop severe acute respiratory distress syndrome (ARDS) and subsequent irreversible lung damage despite extracorporeal membrane oxygenation...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890928/ https://www.ncbi.nlm.nih.gov/pubmed/35251890 http://dx.doi.org/10.1055/s-0042-1742714 |
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author | Koch, Achim Pizanis, Nikolaus Bessa, Vasiliki Herbstreit, Frank Gulbins, Erich Aigner, Clemens Kamler, Markus |
author_facet | Koch, Achim Pizanis, Nikolaus Bessa, Vasiliki Herbstreit, Frank Gulbins, Erich Aigner, Clemens Kamler, Markus |
author_sort | Koch, Achim |
collection | PubMed |
description | Background The majority of patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection present mild symptoms. However, some patients develop severe acute respiratory distress syndrome (ARDS) and subsequent irreversible lung damage despite extracorporeal membrane oxygenation, leaving lung transplantation the ultimate therapeutically option. Case Description Here, we report a case of lung transplantation in a 31-year-old male recipient suffering from post-coronavirus disease 2019 respiratory failure with irreversible ARDS after prolonged extracorporeal membrane oxygenation therapy. Conclusion Patient selection criteria are elucidated. One relevant mechanism for susceptibility to SARS-CoV-2 in the respiratory system, the acid sphingomyelinase/ceramide system might be altered during infection with SARS-CoV-2. |
format | Online Article Text |
id | pubmed-8890928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-88909282022-03-03 Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection Koch, Achim Pizanis, Nikolaus Bessa, Vasiliki Herbstreit, Frank Gulbins, Erich Aigner, Clemens Kamler, Markus Thorac Cardiovasc Surg Rep Background The majority of patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection present mild symptoms. However, some patients develop severe acute respiratory distress syndrome (ARDS) and subsequent irreversible lung damage despite extracorporeal membrane oxygenation, leaving lung transplantation the ultimate therapeutically option. Case Description Here, we report a case of lung transplantation in a 31-year-old male recipient suffering from post-coronavirus disease 2019 respiratory failure with irreversible ARDS after prolonged extracorporeal membrane oxygenation therapy. Conclusion Patient selection criteria are elucidated. One relevant mechanism for susceptibility to SARS-CoV-2 in the respiratory system, the acid sphingomyelinase/ceramide system might be altered during infection with SARS-CoV-2. Georg Thieme Verlag KG 2022-03-02 /pmc/articles/PMC8890928/ /pubmed/35251890 http://dx.doi.org/10.1055/s-0042-1742714 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Koch, Achim Pizanis, Nikolaus Bessa, Vasiliki Herbstreit, Frank Gulbins, Erich Aigner, Clemens Kamler, Markus Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection |
title | Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection |
title_full | Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection |
title_fullStr | Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection |
title_full_unstemmed | Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection |
title_short | Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection |
title_sort | lung transplantation for adult respiratory distress syndrome after sars-cov-2 infection |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890928/ https://www.ncbi.nlm.nih.gov/pubmed/35251890 http://dx.doi.org/10.1055/s-0042-1742714 |
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