Cargando…

Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy

OBJECTIVE: There is limited evidence on feasibility and safety of only heparin rota-flush(OHRF)solution in rotational atherectomy (RA). We compared the safety and efficacy of OHRF solution with alternative rota-flush (ARF) solution in patients who underwent RA. METHODS: A total of 48 patients who un...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandra, Sharad, Choudhary, Rajeev, Chaudhary, Gaurav, Sharma, Akhil, Pradhan, Akshyaya, Bhandari, Monika, Vishwakarma, Pravesh, Sethi, Rishi, Narain, Varun Shankar, Dwivedi, Sudhanshu Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891009/
https://www.ncbi.nlm.nih.gov/pubmed/34883110
http://dx.doi.org/10.1016/j.ihj.2021.12.001
_version_ 1784661778367512576
author Chandra, Sharad
Choudhary, Rajeev
Chaudhary, Gaurav
Sharma, Akhil
Pradhan, Akshyaya
Bhandari, Monika
Vishwakarma, Pravesh
Sethi, Rishi
Narain, Varun Shankar
Dwivedi, Sudhanshu Kumar
author_facet Chandra, Sharad
Choudhary, Rajeev
Chaudhary, Gaurav
Sharma, Akhil
Pradhan, Akshyaya
Bhandari, Monika
Vishwakarma, Pravesh
Sethi, Rishi
Narain, Varun Shankar
Dwivedi, Sudhanshu Kumar
author_sort Chandra, Sharad
collection PubMed
description OBJECTIVE: There is limited evidence on feasibility and safety of only heparin rota-flush(OHRF)solution in rotational atherectomy (RA). We compared the safety and efficacy of OHRF solution with alternative rota-flush (ARF) solution in patients who underwent RA. METHODS: A total of 48 patients who underwent RA were enrolled in the study. In 25 patients OHRF solution and in 23 patients ARF solution was utilized. The study end points were procedural success rateandrota-related adverse cardiovascular event (RRAE) including slow flow, no reflow, bradycardia, and hemodynamic instability. RESULTS: Procedural success was achieved in all patients in both the OHRF and ARF groups. There was no statistically significant difference in RRAE between the two groups(32.0% vs. 34.7%, p = 0.83). CONCLUSION: OHRF solution appears a more simplistic solution while performing rotablation as compared to ARF solution. Side effects such as hypotension and bradycardia can be circumvented with OHRF solution during rotablation.
format Online
Article
Text
id pubmed-8891009
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-88910092022-03-04 Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy Chandra, Sharad Choudhary, Rajeev Chaudhary, Gaurav Sharma, Akhil Pradhan, Akshyaya Bhandari, Monika Vishwakarma, Pravesh Sethi, Rishi Narain, Varun Shankar Dwivedi, Sudhanshu Kumar Indian Heart J Original Article OBJECTIVE: There is limited evidence on feasibility and safety of only heparin rota-flush(OHRF)solution in rotational atherectomy (RA). We compared the safety and efficacy of OHRF solution with alternative rota-flush (ARF) solution in patients who underwent RA. METHODS: A total of 48 patients who underwent RA were enrolled in the study. In 25 patients OHRF solution and in 23 patients ARF solution was utilized. The study end points were procedural success rateandrota-related adverse cardiovascular event (RRAE) including slow flow, no reflow, bradycardia, and hemodynamic instability. RESULTS: Procedural success was achieved in all patients in both the OHRF and ARF groups. There was no statistically significant difference in RRAE between the two groups(32.0% vs. 34.7%, p = 0.83). CONCLUSION: OHRF solution appears a more simplistic solution while performing rotablation as compared to ARF solution. Side effects such as hypotension and bradycardia can be circumvented with OHRF solution during rotablation. Elsevier 2022 2021-12-06 /pmc/articles/PMC8891009/ /pubmed/34883110 http://dx.doi.org/10.1016/j.ihj.2021.12.001 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Chandra, Sharad
Choudhary, Rajeev
Chaudhary, Gaurav
Sharma, Akhil
Pradhan, Akshyaya
Bhandari, Monika
Vishwakarma, Pravesh
Sethi, Rishi
Narain, Varun Shankar
Dwivedi, Sudhanshu Kumar
Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
title Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
title_full Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
title_fullStr Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
title_full_unstemmed Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
title_short Evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
title_sort evaluation of only heparin-based rota-flush solution against alternative rota-flush solution in patients with severe coronary artery calcification undergoing rotational atherectomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891009/
https://www.ncbi.nlm.nih.gov/pubmed/34883110
http://dx.doi.org/10.1016/j.ihj.2021.12.001
work_keys_str_mv AT chandrasharad evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT choudharyrajeev evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT chaudharygaurav evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT sharmaakhil evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT pradhanakshyaya evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT bhandarimonika evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT vishwakarmapravesh evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT sethirishi evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT narainvarunshankar evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy
AT dwivedisudhanshukumar evaluationofonlyheparinbasedrotaflushsolutionagainstalternativerotaflushsolutioninpatientswithseverecoronaryarterycalcificationundergoingrotationalatherectomy