Cargando…
Effective drug combinations in breast, colon and pancreatic cancer cells
Combinations of anti-cancer drugs can overcome resistance and provide new treatments(1,2). The number of possible drug combinations vastly exceeds what could be tested clinically. Efforts to systematically identify active combinations and the tissues and molecular contexts in which they are most eff...
Autores principales: | Jaaks, Patricia, Coker, Elizabeth A., Vis, Daniel J., Edwards, Olivia, Carpenter, Emma F., Leto, Simonetta M., Dwane, Lisa, Sassi, Francesco, Lightfoot, Howard, Barthorpe, Syd, van der Meer, Dieudonne, Yang, Wanjuan, Beck, Alexandra, Mironenko, Tatiana, Hall, Caitlin, Hall, James, Mali, Iman, Richardson, Laura, Tolley, Charlotte, Morris, James, Thomas, Frances, Lleshi, Ermira, Aben, Nanne, Benes, Cyril H., Bertotti, Andrea, Trusolino, Livio, Wessels, Lodewyk, Garnett, Mathew J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891012/ https://www.ncbi.nlm.nih.gov/pubmed/35197630 http://dx.doi.org/10.1038/s41586-022-04437-2 |
Ejemplares similares
-
Cell Model Passports—a hub for clinical, genetic and functional datasets of preclinical cancer models
por: van der Meer, Dieudonne, et al.
Publicado: (2019) -
Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens
por: Gonçalves, Emanuel, et al.
Publicado: (2020) -
Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets
por: Dwane, Lisa, et al.
Publicado: (2020) -
Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing’s Sarcoma
por: Gill, Sonja J., et al.
Publicado: (2015) -
Integrated cross-study datasets of genetic dependencies in cancer
por: Pacini, Clare, et al.
Publicado: (2021)