Microfluidic tool for rapid functional characterization of CRISPR complexes

RNA guided nucleases are regarded as the future genome editing technologies. As such, they need to meet strong safety margins. Two major challenges in incorporating CRISPR technologies into the clinical world are off-target activity and editing efficiency. The common way to tackle such issues is to...

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Detalles Bibliográficos
Autores principales: Peleg-Chen, Dana, Shuvali, Guy, Brio, Lev, Ifrach, Amit, Iancu, Ortal, Barbiro-Michaely, Efrat, Hendel, Ayal, Gerber, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Full length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891023/
https://www.ncbi.nlm.nih.gov/pubmed/35026470
http://dx.doi.org/10.1016/j.nbt.2022.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891023/
https://www.ncbi.nlm.nih.gov/pubmed/35026470
http://dx.doi.org/10.1016/j.nbt.2022.01.003

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