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Microfluidic tool for rapid functional characterization of CRISPR complexes
RNA guided nucleases are regarded as the future genome editing technologies. As such, they need to meet strong safety margins. Two major challenges in incorporating CRISPR technologies into the clinical world are off-target activity and editing efficiency. The common way to tackle such issues is to...
Autores principales: | Peleg-Chen, Dana, Shuvali, Guy, Brio, Lev, Ifrach, Amit, Iancu, Ortal, Barbiro-Michaely, Efrat, Hendel, Ayal, Gerber, Doron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891023/ https://www.ncbi.nlm.nih.gov/pubmed/35026470 http://dx.doi.org/10.1016/j.nbt.2022.01.003 |
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