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Chenodeoxycholic Acid Enhances the Effect of Sorafenib in Inhibiting HepG2 Cell Growth Through EGFR/Stat3 Pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is a highly invasive disease with a high mortality rate. Our previous study found that Chenodeoxycholic acid (CDCA) as an endogenous metabolite can enhance the anti-tumor effect. Sorafenib has limited overall efficacy as a first-line agent in HCC, and combi...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang, Zhang, Yan, Shi, Xiao-Jun, Li, Jun-Xiang, Wang, Lin-Heng, Xie, Chun-E, Wang, Yun-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891169/ https://www.ncbi.nlm.nih.gov/pubmed/35252007 http://dx.doi.org/10.3389/fonc.2022.836333

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