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Evaluation of phototoxicity induced by the anticancer drug rucaparib
Rucaparib (RCP) is a potent selective inhibitor of both PARP-1 and PARP-2 enzymes that induces synthetic lethality in cancer cells. It is used for the treatment of breast and ovarian tumors harboring deleterious germline or somatic cancer susceptibility genes mutations. Although RCP has an indole ch...
Autores principales: | Mateos-Pujante, Alejandro, Jiménez, María Consuelo, Andreu, Inmaculada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891269/ https://www.ncbi.nlm.nih.gov/pubmed/35236893 http://dx.doi.org/10.1038/s41598-022-07319-9 |
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