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Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis

Leishmaniasis is a neglected protozoan disease affecting over 12 million people globally with no approved vaccines for human use. New World cutaneous leishmaniasis (CL) caused by L. mexicana is characterized by the development of chronic non-healing skin lesions. Using the CRISPR/Cas9 technique, we...

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Detalles Bibliográficos
Autores principales:	Volpedo, Greta, Pacheco-Fernandez, Thalia, Holcomb, Erin A., Zhang, Wen-Wei, Lypaczewski, Patrick, Cox, Blake, Fultz, Rebecca, Mishan, Chelsea, Verma, Chaitenya, Huston, Ryan H., Wharton, Abigail R., Dey, Ranadhir, Karmakar, Subir, Oghumu, Steve, Hamano, Shinjiro, Gannavaram, Sreenivas, Nakhasi, Hira L., Matlashewski, Greg, Satoskar, Abhay R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891280/ https://www.ncbi.nlm.nih.gov/pubmed/35236861 http://dx.doi.org/10.1038/s41541-022-00449-1

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