NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma

Multiple myeloma (MM) remains an incurable plasma cell cancer characterized by abnormal secretion of monoclonal immunoglobulins. The molecular mechanism that regulates the drug sensitivity of MM cells is being intensively studied. Here, we report an unexpected finding that the protein encoded by neu...

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Detalles Bibliográficos
Autores principales: Huang, Xi, Cao, Wen, Yao, Shunnan, Chen, Jing, Liu, Yang, Qu, Jianwei, Li, Yi, Han, Xiaoyan, He, Jingsong, Huang, He, Zhang, Enfan, Cai, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891287/
https://www.ncbi.nlm.nih.gov/pubmed/35236820
http://dx.doi.org/10.1038/s41419-022-04629-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891287/
https://www.ncbi.nlm.nih.gov/pubmed/35236820
http://dx.doi.org/10.1038/s41419-022-04629-8

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