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Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution
Most COVID-19 vaccines require temperature control for transportation and storage. Two types of vaccine have been developed by manufacturers (Pfizer and Moderna). Both vaccines are based on mRNA and lipid nanoparticles requiring low temperature storage. The Pfizer vaccine requires ultra-low temperat...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891306/ https://www.ncbi.nlm.nih.gov/pubmed/35236859 http://dx.doi.org/10.1038/s41597-022-01167-y |
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author | Sun, Jian Zhang, Mingkan Gehl, Anthony Fricke, Brian Nawaz, Kashif Gluesenkamp, Kyle Shen, Bo Munk, Jeff Hagerman, Joe Lapsa, Melissa Awwad, Nader Recipe, Chris Auyer, Doug Brisson, David |
author_facet | Sun, Jian Zhang, Mingkan Gehl, Anthony Fricke, Brian Nawaz, Kashif Gluesenkamp, Kyle Shen, Bo Munk, Jeff Hagerman, Joe Lapsa, Melissa Awwad, Nader Recipe, Chris Auyer, Doug Brisson, David |
author_sort | Sun, Jian |
collection | PubMed |
description | Most COVID-19 vaccines require temperature control for transportation and storage. Two types of vaccine have been developed by manufacturers (Pfizer and Moderna). Both vaccines are based on mRNA and lipid nanoparticles requiring low temperature storage. The Pfizer vaccine requires ultra-low temperature storage (−80 °C to −60 °C), while the Moderna vaccine requires −30 °C storage. However, the last stage of distribution is quite challenging, especially for rural or suburban areas, where local towns, pharmacy chains and hospitals may not have the infrastructure required to store the vaccine at the required temperature. In addition, there is limited data available to address ancillary challenges of the distribution framework for both transportation and storage stages, including safety concerns due to human exposure to large amounts of CO(2) from dry-ice sublimation, issues due to the pressure increase caused by dry-ice sublimation, and the potential issue caused by non-uniform cryogenic temperatures. As such, there is a need for test dataset to assist the development of a quick, effective, secure, and safe solution to mitigate the challenges faced by vaccine distribution logistics. |
format | Online Article Text |
id | pubmed-8891306 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-88913062022-03-17 Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution Sun, Jian Zhang, Mingkan Gehl, Anthony Fricke, Brian Nawaz, Kashif Gluesenkamp, Kyle Shen, Bo Munk, Jeff Hagerman, Joe Lapsa, Melissa Awwad, Nader Recipe, Chris Auyer, Doug Brisson, David Sci Data Data Descriptor Most COVID-19 vaccines require temperature control for transportation and storage. Two types of vaccine have been developed by manufacturers (Pfizer and Moderna). Both vaccines are based on mRNA and lipid nanoparticles requiring low temperature storage. The Pfizer vaccine requires ultra-low temperature storage (−80 °C to −60 °C), while the Moderna vaccine requires −30 °C storage. However, the last stage of distribution is quite challenging, especially for rural or suburban areas, where local towns, pharmacy chains and hospitals may not have the infrastructure required to store the vaccine at the required temperature. In addition, there is limited data available to address ancillary challenges of the distribution framework for both transportation and storage stages, including safety concerns due to human exposure to large amounts of CO(2) from dry-ice sublimation, issues due to the pressure increase caused by dry-ice sublimation, and the potential issue caused by non-uniform cryogenic temperatures. As such, there is a need for test dataset to assist the development of a quick, effective, secure, and safe solution to mitigate the challenges faced by vaccine distribution logistics. Nature Publishing Group UK 2022-03-02 /pmc/articles/PMC8891306/ /pubmed/35236859 http://dx.doi.org/10.1038/s41597-022-01167-y Text en © This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) applies to the metadata files associated with this article. |
spellingShingle | Data Descriptor Sun, Jian Zhang, Mingkan Gehl, Anthony Fricke, Brian Nawaz, Kashif Gluesenkamp, Kyle Shen, Bo Munk, Jeff Hagerman, Joe Lapsa, Melissa Awwad, Nader Recipe, Chris Auyer, Doug Brisson, David Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution |
title | Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution |
title_full | Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution |
title_fullStr | Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution |
title_full_unstemmed | Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution |
title_short | Dataset of ultralow temperature refrigeration for COVID 19 vaccine distribution solution |
title_sort | dataset of ultralow temperature refrigeration for covid 19 vaccine distribution solution |
topic | Data Descriptor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891306/ https://www.ncbi.nlm.nih.gov/pubmed/35236859 http://dx.doi.org/10.1038/s41597-022-01167-y |
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