A nation-wide twin study of social cognition in schizophrenia spectrum disorders

We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in th...

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Autores principales: Lemvigh, Cecilie K., Glenthøj, Birte Y., Fagerlund, Birgitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891357/
https://www.ncbi.nlm.nih.gov/pubmed/35236855
http://dx.doi.org/10.1038/s41537-022-00223-1
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author Lemvigh, Cecilie K.
Glenthøj, Birte Y.
Fagerlund, Birgitte
author_facet Lemvigh, Cecilie K.
Glenthøj, Birte Y.
Fagerlund, Birgitte
author_sort Lemvigh, Cecilie K.
collection PubMed
description We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in the ability to detect sarcasm. Impairments were also observed in the unaffected MZ co-twins, indicating that social cognitive deficits could be a genetic vulnerability indicator of the disease. Worse social cognition was associated with lower intelligence and higher levels of psychopathology in patients.
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spelling pubmed-88913572022-03-08 A nation-wide twin study of social cognition in schizophrenia spectrum disorders Lemvigh, Cecilie K. Glenthøj, Birte Y. Fagerlund, Birgitte Schizophrenia (Heidelb) Brief Communication We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in the ability to detect sarcasm. Impairments were also observed in the unaffected MZ co-twins, indicating that social cognitive deficits could be a genetic vulnerability indicator of the disease. Worse social cognition was associated with lower intelligence and higher levels of psychopathology in patients. Nature Publishing Group UK 2022-03-02 /pmc/articles/PMC8891357/ /pubmed/35236855 http://dx.doi.org/10.1038/s41537-022-00223-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Communication
Lemvigh, Cecilie K.
Glenthøj, Birte Y.
Fagerlund, Birgitte
A nation-wide twin study of social cognition in schizophrenia spectrum disorders
title A nation-wide twin study of social cognition in schizophrenia spectrum disorders
title_full A nation-wide twin study of social cognition in schizophrenia spectrum disorders
title_fullStr A nation-wide twin study of social cognition in schizophrenia spectrum disorders
title_full_unstemmed A nation-wide twin study of social cognition in schizophrenia spectrum disorders
title_short A nation-wide twin study of social cognition in schizophrenia spectrum disorders
title_sort nation-wide twin study of social cognition in schizophrenia spectrum disorders
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891357/
https://www.ncbi.nlm.nih.gov/pubmed/35236855
http://dx.doi.org/10.1038/s41537-022-00223-1
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