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How Naive T-Cell Clone Counts Are Shaped By Heterogeneous Thymic Output and Homeostatic Proliferation

The specificity of T cells is that each T cell has only one T cell receptor (TCR). A T cell clone represents a collection of T cells with the same TCR sequence. Thus, the number of different T cell clones in an organism reflects the number of different T cell receptors (TCRs) that arise from recombi...

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Detalles Bibliográficos
Autores principales: Dessalles, Renaud, Pan, Yunbei, Xia, Mingtao, Maestrini, Davide, D’Orsogna, Maria R., Chou, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891377/
https://www.ncbi.nlm.nih.gov/pubmed/35250963
http://dx.doi.org/10.3389/fimmu.2021.735135