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How Naive T-Cell Clone Counts Are Shaped By Heterogeneous Thymic Output and Homeostatic Proliferation
The specificity of T cells is that each T cell has only one T cell receptor (TCR). A T cell clone represents a collection of T cells with the same TCR sequence. Thus, the number of different T cell clones in an organism reflects the number of different T cell receptors (TCRs) that arise from recombi...
Autores principales: | Dessalles, Renaud, Pan, Yunbei, Xia, Mingtao, Maestrini, Davide, D’Orsogna, Maria R., Chou, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891377/ https://www.ncbi.nlm.nih.gov/pubmed/35250963 http://dx.doi.org/10.3389/fimmu.2021.735135 |
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