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The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series

Spinal cord injury (SCI) is a devastating condition that impacts multiple organ systems. Neurogenic bowel dysfunction (NBD) frequently occurs after a SCI leading to reduced sensation of bowel fullness and bowel movement often leading to constipation or fecal incontinence. Spinal Neuromodulation has...

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Autores principales: Kreydin, Evgeniy, Zhong, Hui, Lavrov, Igor, Edgerton, V. Reggie, Gad, Parag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891530/
https://www.ncbi.nlm.nih.gov/pubmed/35250456
http://dx.doi.org/10.3389/fnins.2022.816106
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author Kreydin, Evgeniy
Zhong, Hui
Lavrov, Igor
Edgerton, V. Reggie
Gad, Parag
author_facet Kreydin, Evgeniy
Zhong, Hui
Lavrov, Igor
Edgerton, V. Reggie
Gad, Parag
author_sort Kreydin, Evgeniy
collection PubMed
description Spinal cord injury (SCI) is a devastating condition that impacts multiple organ systems. Neurogenic bowel dysfunction (NBD) frequently occurs after a SCI leading to reduced sensation of bowel fullness and bowel movement often leading to constipation or fecal incontinence. Spinal Neuromodulation has been proven to be a successful modality to improve sensorimotor and autonomic function in patients with spinal cord injuries. The pilot data presented here represents the first demonstration of using spinal neuromodulation to activate the anorectal regions of patients with spinal cord injuries and the acute and chronic effects of stimulation. We observed that spinal stimulation induces contractions as well as changes in sensation and pressure profiles along the length of the anorectal region. In addition, we present a case report of a patient with a SCI and the beneficial effect of spinal neuromodulation on the patient’s bowel program.
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spelling pubmed-88915302022-03-04 The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series Kreydin, Evgeniy Zhong, Hui Lavrov, Igor Edgerton, V. Reggie Gad, Parag Front Neurosci Neuroscience Spinal cord injury (SCI) is a devastating condition that impacts multiple organ systems. Neurogenic bowel dysfunction (NBD) frequently occurs after a SCI leading to reduced sensation of bowel fullness and bowel movement often leading to constipation or fecal incontinence. Spinal Neuromodulation has been proven to be a successful modality to improve sensorimotor and autonomic function in patients with spinal cord injuries. The pilot data presented here represents the first demonstration of using spinal neuromodulation to activate the anorectal regions of patients with spinal cord injuries and the acute and chronic effects of stimulation. We observed that spinal stimulation induces contractions as well as changes in sensation and pressure profiles along the length of the anorectal region. In addition, we present a case report of a patient with a SCI and the beneficial effect of spinal neuromodulation on the patient’s bowel program. Frontiers Media S.A. 2022-02-17 /pmc/articles/PMC8891530/ /pubmed/35250456 http://dx.doi.org/10.3389/fnins.2022.816106 Text en Copyright © 2022 Kreydin, Zhong, Lavrov, Edgerton and Gad. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kreydin, Evgeniy
Zhong, Hui
Lavrov, Igor
Edgerton, V. Reggie
Gad, Parag
The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series
title The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series
title_full The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series
title_fullStr The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series
title_full_unstemmed The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series
title_short The Effect of Non-invasive Spinal Cord Stimulation on Anorectal Function in Individuals With Spinal Cord Injury: A Case Series
title_sort effect of non-invasive spinal cord stimulation on anorectal function in individuals with spinal cord injury: a case series
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891530/
https://www.ncbi.nlm.nih.gov/pubmed/35250456
http://dx.doi.org/10.3389/fnins.2022.816106
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